Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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![Compound
1.
2.
3.
carriers (1)
4.
5.
morphine
Codeine
pka (Strongest Acidic)
pka (Strongest Basic)
Log P
0.87
1.39
Oxycodone
Hydromorphone
Heroin (diamorphine)
What does the pKa value tell about each of the compounds?
0,7
1,06
1158
10 17
9.08
pka
ChemAzon
8,21 (at 25°C)
812
strong acidic 13,57 strongest Basic B. 11
8₁2
7,95 at 25°C
Why is the balance between water and lipid solubility of a drug important?](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F0cdac48b-df9c-42f7-ad41-c38576f97b3e%2F6533ff70-c9cc-42e0-9b2f-d0abc4b559a0%2Fa4kwuv7_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Compound
1.
2.
3.
carriers (1)
4.
5.
morphine
Codeine
pka (Strongest Acidic)
pka (Strongest Basic)
Log P
0.87
1.39
Oxycodone
Hydromorphone
Heroin (diamorphine)
What does the pKa value tell about each of the compounds?
0,7
1,06
1158
10 17
9.08
pka
ChemAzon
8,21 (at 25°C)
812
strong acidic 13,57 strongest Basic B. 11
8₁2
7,95 at 25°C
Why is the balance between water and lipid solubility of a drug important?
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