For part C of this lab, during the work up, we add 30% KOH solution. What is the purpose of adding 30% KOH during the work up? Part C: a-Diethylamino-2,6-dimethylacetanilide H₂C. HN CH₂C CH₂ (CHNH H₂C. HN mp 68-69 lidocaine O It deprotonates the lidocaine O It decreases the pH, thus making the product less soluble CH₂N(C₂Hz O It creates the lidocaine salt O It increases the solubility of lidocaine in aqueous phase CH₂
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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