21. The melting points (mp) of three beta agonist homologues are given below OH HO. ОН Terbutaline mp 119-122°C HO. OH HY OH

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
Question
21. The melting points (mp) of three beta agonist homologues are given below
OH
HO
OH
Terbutaline mp 119-122°C
OH
zey
HO.
OH
Metaproterenol mp 100°C
НО.
HO
OH H
N
Isoproterenol mp 155.5°C
What is their expected order of solubility in water, from lowest to
highest?
A. Terbutaline>metaproterenol>isoproterenol
B. Metaproterenol>terbutaline>isoproterenol
C. Isoproterenol>metaproterenol>terbutaline
D. Isoproterenol>terbutaline>metaproterenol
E. Metaproterenol>isoproterenol>terbutaline
26. The melting point of isosorbide-2,5-diaspirinate is higher than that of
aspirin. What is the significance of higher melting point in preformulation?
A. High melting point is generally associated with low aqueous solubility
B. High melting point is generally associated with high aqueous solubility
C. Melting point is inversely proportional to density
D. Melting point is used in the calculation of viscosity
E. A high melting point indicates better chemical and physical stability in
aqueous solution
Transcribed Image Text:21. The melting points (mp) of three beta agonist homologues are given below OH HO OH Terbutaline mp 119-122°C OH zey HO. OH Metaproterenol mp 100°C НО. HO OH H N Isoproterenol mp 155.5°C What is their expected order of solubility in water, from lowest to highest? A. Terbutaline>metaproterenol>isoproterenol B. Metaproterenol>terbutaline>isoproterenol C. Isoproterenol>metaproterenol>terbutaline D. Isoproterenol>terbutaline>metaproterenol E. Metaproterenol>isoproterenol>terbutaline 26. The melting point of isosorbide-2,5-diaspirinate is higher than that of aspirin. What is the significance of higher melting point in preformulation? A. High melting point is generally associated with low aqueous solubility B. High melting point is generally associated with high aqueous solubility C. Melting point is inversely proportional to density D. Melting point is used in the calculation of viscosity E. A high melting point indicates better chemical and physical stability in aqueous solution
Expert Solution
steps

Step by step

Solved in 5 steps

Blurred answer
Knowledge Booster
NMR Spectroscopy of Organic Molecules
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY