The TRP operon is regulated by two mechanisms, the TrpR regulatory protein and attenuation.  Complete following sentences by picking the right choice:  1. Attenuation occurs in the   ___________ (promoter, structural genes, 5' UTR, region upstream of the promoter) , which is divided into four regions. It depends on the amount of    ___________ (trp, tRNAs, charged trp tRNAs)  in the cell, which is the signal for this type of regulation.  2. If the signal is low in the cell, then the ribosome pauses in region    _______ (1, 2, 3, or 4)  because the sequence includes several    ______ (start codons, sotp codons, trp codons, trp molecules, inverted complementary sequences). Regions   ________ (1 and 4, 1 and 3, 2 and 3, 2 and 4, 1 and 2, 3 and 4) will form a secondary structure and ______ (tranlsation continues, transcription stops, transcription continues, translation stops)  (choose the first process impacted).   3. If the signal is high in the cell, then regions   ______ (2 and 3, 2 and 4, 1 and 4, 1 and 3, 3 and 4, 1 and 2)  pair up and  _____ (tranlsation continues, transcription stops, transcription continues, translation stops).    4. When expression is stopped, this occurs because region 4 is followed by a   ______ (rut sequence, sequence with many A-U pairs), which will make this behave as a rho-independent terminator.

Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter14: Gene Regulation
Section: Chapter Questions
Problem 11TYU
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The TRP operon is regulated by two mechanisms, the TrpR regulatory protein and attenuation. 

Complete following sentences by picking the right choice: 

1. Attenuation occurs in the   ___________ (promoter, structural genes, 5' UTR, region upstream of the promoter) , which is divided into four regions. It depends on the amount of    ___________ (trp, tRNAs, charged trp tRNAs)  in the cell, which is the signal for this type of regulation. 

2. If the signal is low in the cell, then the ribosome pauses in region    _______ (1, 2, 3, or 4)  because the sequence includes several    ______ (start codons, sotp codons, trp codons, trp molecules, inverted complementary sequences). Regions   ________ (1 and 4, 1 and 3, 2 and 3, 2 and 4, 1 and 2, 3 and 4) will form a secondary structure and ______ (tranlsation continues, transcription stops, transcription continues, translation stops)  (choose the first process impacted).

 

3. If the signal is high in the cell, then regions   ______ (2 and 3, 2 and 4, 1 and 4, 1 and 3, 3 and 4, 1 and 2)  pair up and  _____ (tranlsation continues, transcription stops, transcription continues, translation stops). 

 

4. When expression is stopped, this occurs because region 4 is followed by a   ______ (rut sequence, sequence with many A-U pairs), which will make this behave as a rho-independent terminator.

 

 

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