The structure below shows that of a polypeptide composed of multiple amino acid residues, some of which have undergone post-translational modifications in their side chains. NH2 residues. 1) This polypeptide has 2) Using one-letter abbreviations, the sequence of the polypeptide (before post-translational modification) is

Q: B14. The last two amino acids added to a polypeptide are - Trp - Glu - (C terminus). The last two…

A: To determine the last two anticodons used in the translation of the given polypeptide sequence, we…

Q: (b) r , The following polypeptide sequence has three alpha helices and two B turns. Based on what we…

A: An amino group and an acid group-containing organic molecules are called Amino acids.…

Q: Glycosylation is a major type of protein post-translational modification. Identify the amino acid…

A: Cavalent or generally enzymatic reactions takr place after or during translation are termed as post…

Q: Isoleucine is encoded by three codons (5')AUU, (5')AUC, and (5')AUA. These three codons are…

A: Wobble hypothesis: This hypothesis was given by Francis Crick. According to this hypothesis the…

Q: 1 0.8 0.6 Mutant y 0.4 Wild-Type 0.2 40 60 80 [ligand] 20

A: According to the given information, the wild type protein structure has aspartate in its primary…

Q: Ornithine is structurally similar to lysine except ornithine’s side chain is one methylene group…

A: Ornithine plays important role in urea cycle. Ornithine is structurally similar to lysine except…

Q: Post-translational modification of proteins refers to the covalent and  enzymatic modification of…

A: The translation is a process by which the proteins are synthesized from the RNA. RNA polymerase and…

Q: Which amino acid residue is preferred at which position in the following peptide for cleavage by…

A: While writing a polypeptide, the left side is the N terminus and the right side is the C terminus.

Q: Pompe disease is a rare genetic condition resulting from a deficiency of the protein…

A: Pompe disease is a genetic disorder that involves the accumulation of glycogen inside the cells.…

Q: They are related in str They have identical ba C) they are the result of a

A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…

Q: Briefly describe each of the following possible posttranslational protein modifications.  Give an…

A: The deoxyribonucleic acid (DNA) is the genetic material of the organism that is transcripted to form…

Q: what is post-translational protein covalent modification? give three examples and name the enzyme…

A: Protein post-translational modifications (PMTs) increase the functional diversity of the proteome by…

Q: The following RNA sequence represents a small messenger which can be translated in a prokaryotic…

A: The first step in translating an RNA sequence into a protein is to divide the sequence into codons,…

Q: Some mutations affect changes in protein structure and function that can result in disease whereas…

A: The DNA (deoxyribonucleic acid) is the genetic material of an organism. The DNA is inherited by the…

Q: Consider the following coding 71 nucleotide DNA template sequence (It does not contain a…

A: In cell protein formed according to the sequence on mRNA. mRNA is formed from DNA sequence by the…

Q: Consider the following in light of the concept of levels of structure (primary, secondary, tertiary,…

A: In double stranded DNA structure two strands run in anti-parallel directions through base pairing…

Q: Remembering that the amino acid side chains projecting from each polypeptide backbone in a β sheet…

A: Amongst secondary structures of polypeptide chains made of amino acids, β-sheets are a more spacious…

Q: On average, how many phosphoanhydride bonds (P;-P; bonds) are directly hydrolyzed in the course of…

A: As per the central dogma of molecular biology, genetic information is stored in the DNA. The genetic…

Q: Gene editing is also used to explore the structure and function ofproteins. For example, changes can…

A: From the observations, it gets clear that the amino acid aspartate shows the most functional…

Q: Lactose permease, a protein of E. coli, is composed of a single polypeptide that is 417 amino acids…

A: Lactose permease Its belong to transmembrane protein family. The transport mechanism of lactose…

Q: What polypeptides would be formed from the sequence UCAATGGGGUUUAUAGCG… (there are bases after the…

A: Ribonucleic acid (RNA) is a nucleic acid found in both the nucleus and cytoplasm. It can be genetic…

Q: Translate each changed sequence. Does the mutation result in a change in the amino acid sequence? If…

A: The genetic codon present in the mRNA will be translated into polypeptide chain by ribosome during…

Q: Consider a mutation that results in a substitution of Cysteine (CYS) ) for Tyrosine (TYR) at…

A: Cysteine is a polar amino acid.  Cysteine is a triprotic acid with three ionizable functional…

Q: A normal polypeptide and a mutant of the polypeptide were hydrolyzed by an endopeptidase under the…

A: Chromatography is a useful technique to study the separation of amino acids. Paper chromatography is…

Q: Consider a short peptide that forms an alpha-helix within a larger protein structure. Suppose that…

A: Amino acids are the simplest units to form peptides and proteins. The amino acid sequences represent…

Q: Changing one amino acid within a protein sequence from a tryptophan to a stop codon would be best…

A: Mutation is the change in the nucleotide sequence of the DNA that causes a change in the mRNA.…

Q: Using the given information, determine the correct order of the following events during translation:

A:

Q: you were given an unknown peptide. Explain in detail how you would determine the amino acid sequence…

A: The amino acids that form the protein are mostly L forms. The carboxyl group of amino acids in the…

Q: The synthesis of a peptide is given by the mRNA sequence 5'GAAGAGAAACUUACU3', Find the primary…

A: The 'Central Dogma' is the process by which the instructions in DNA are converted into a functional…

Q: What RNA base sequence is complimentary to the following DNA base sequence 5'-CATGATTAT-3'? Using…

A: Gene expression is the process through which the genetic codes of a gene, the nucleotide sequence,…

Q: Cystic fibrosis (CF) is an inherited disorder caused by different types of mutations, many of which…

A: CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator…

Q: rotein after a post-trans o other changes in the o

A: There will be more conjugate base because it makes a favorable hydrogen bond to the phosphate .

Q: In the protein adenylate kinase, the C-terminal region has the sequence Val-Asp-Asp-Val-Phe-…

A: A helical wheel representation is a type of plot or visual representation used to illustrate the…

Q: Arrange the following steps in correct sequence. Translation 1. Formation of the peptide bond 2.…

A: The nucleotide is the most fundamental component of nucleic acids. The polymers RNA and DNA are made…

Q: To visualize the spatial arrangement of amino acid residues in an a-helix, it is helpful to imagine…

A: Alpha helix is a secondary structure of protein. The alpha-helix can be right-handed or left-handed.…

Q: The antibacterial protein colicin E3 is an effective inhibitor of pro- tein synthesis in…

A: It is given that the protein colicin E13 is an effective inhibitor of the protein synthesis in…

Q: Most proteins have more leucine than histidine residues, but more histidine than tryptophan…

A: A genetic code is a set of three nucleotides.

Q: Explain how a peptide bond is formed in translation elongation in terms of: a) Which enzyme…

A: Introduction  Peptide bonds are covalent bonds that link two amino acids together to form a peptide…

Q: What kind of bond is created between successive amino acids in a protein? If there are more codon…

A: Proteins are made up of chemical 'building blocks' called amino acids. Nucleotide is the basic…

Genomics

Genes are responsible for transmitting the characters located on the chromosomes from one individual to another across the generations. Genetics is the study of different genes that are involved in different functions. Genetics is a branch of biology that studies genes, genetic diversity, and heredity in living organisms. The genetic system consists of genetic notations, which is a system of signs and symbols. Genotype refers to the organism's genetic composition, and phenotype refers to the observable property of the organism.