Gene editing is also used to explore the structure and function ofproteins. For example, changes can be made to the coding sequenceof a gene to determine how alterations in the amino acid sequenceaffect the function of a protein. Let’s suppose that you areinterested in the functional importance of a particular glutamicacid (an amino acid) within a protein you are studying. By geneediting, you make mutant proteins in which the glutamic acidcodon has been changed to other codons. You then test the encodedmutant proteins for functionality. The results are as follows: FunctionalityNormal protein 100%Mutant proteins containingTyrosine 5%Phenylalanine 3%Aspartic acid 94%Glycine 4%From these results, what would you conclude about the functionalsignificance of this glutamic acid within the protein?
Gene editing is also used to explore the structure and function of
proteins. For example, changes can be made to the coding sequence
of a gene to determine how alterations in the amino acid sequence
affect the function of a protein. Let’s suppose that you are
interested in the functional importance of a particular glutamic
acid (an amino acid) within a protein you are studying. By gene
editing, you make mutant proteins in which the glutamic acid
codon has been changed to other codons. You then test the encoded
mutant proteins for functionality. The results are as follows:
Functionality
Normal protein 100%
Mutant proteins containing
Tyrosine 5%
Phenylalanine 3%
Aspartic acid 94%
Glycine 4%
From these results, what would you conclude about the functional
significance of this glutamic acid within the protein?
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