The Robinson annulation is a combination of two carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation. The most common partners in the reaction are a nucleophilic donor (such as a cyclic ketone, a B-keto ester, an enamine, or a B-diketone) and an a6-unsaturated ketone acceptor. The product is a substituted 2-cyclohexenone derivative. Draw the structures of the nucleophilic B-diketone and the aB-unsaturated ketone acceptor that were combined in a Robinson annulation to give the following product: Ph opy ato
The Robinson annulation is a combination of two carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation. The most common partners in the reaction are a nucleophilic donor (such as a cyclic ketone, a B-keto ester, an enamine, or a B-diketone) and an a6-unsaturated ketone acceptor. The product is a substituted 2-cyclohexenone derivative. Draw the structures of the nucleophilic B-diketone and the aB-unsaturated ketone acceptor that were combined in a Robinson annulation to give the following product: Ph opy ato
Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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![The Robinson annulation is a combination of two carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation. The most common partners in the reaction are a
nucleophilic donor (such as a cyclic ketone, a ß-keto ester, an enamine, or a 6-diketone) and an a 6-unsaturated ketone acceptor The product is a substituted 2-cyclohexenone derivative.
Draw the structures of the nucleophilic B-diketone and the a B-unsaturated ketone acceptor that wvere combined in a Robinson annulation to give the following product:
Ph
C P
000- IF](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fc8ea2db0-7475-4a7d-bef3-e03d95cf57eb%2F1e68f80d-dc42-4b47-bf9c-63360399a703%2Fm3tjwfc_processed.jpeg&w=3840&q=75)
Transcribed Image Text:The Robinson annulation is a combination of two carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation. The most common partners in the reaction are a
nucleophilic donor (such as a cyclic ketone, a ß-keto ester, an enamine, or a 6-diketone) and an a 6-unsaturated ketone acceptor The product is a substituted 2-cyclohexenone derivative.
Draw the structures of the nucleophilic B-diketone and the a B-unsaturated ketone acceptor that wvere combined in a Robinson annulation to give the following product:
Ph
C P
000- IF
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