The population risk of NIDDM is highly dependent on the population under consideration; in most populations, this risk is 1%-5%, although it is 6% to 7% in the United States. If a patient has one affected sibling, the risk increases to 10%; an affected sibling and another first-degree relative, the risk is 20%; an affected monozygotic twin, the risk is 50%-100%. 1) Is this a single gene inheritance or multifactorial disease? 2) Is there a strong genetic or environmental cause to the development of this disease? If both genetic and environmental causes are implicated, you have to indicate each of them separately.
The population risk of NIDDM is highly dependent on the population under consideration; in most populations, this risk is 1%-5%, although it is 6% to 7% in the United States. If a patient has one affected sibling, the risk increases to 10%; an affected sibling and another first-degree relative, the risk is 20%; an affected monozygotic twin, the risk is 50%-100%.
1) Is this a single gene inheritance or multifactorial disease?
2) Is there a strong genetic or environmental cause to the development of this disease? If both genetic and environmental causes are implicated, you have to indicate each of them separately.
1&2)
Non-Insulin Dependent Diabetes Mellitus (NIDDM), also known as type 2 diabetes, is a common metabolic disorder that affects millions of people worldwide. It is characterized by high blood sugar levels and insulin resistance, and can lead to a range of serious health complications if left untreated. The exact causes of NIDDM are not yet fully understood, but a combination of genetic and environmental factors are known to play a role in its development. Understanding the risk factors for NIDDM is important in order to develop effective strategies for preventing and managing this disease.
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