Uncle 1 Cousin 1 A = normal allele Grandma 1 Aunt 1 Grandpa 1 Mom Sister 1 a = albino allele Affected Individual O Grandma 2 Dad Sister 2 Aunt 2 Grandpa 2 Uncle 2 Cousin 2 Aunt 3
Uncle 1 Cousin 1 A = normal allele Grandma 1 Aunt 1 Grandpa 1 Mom Sister 1 a = albino allele Affected Individual O Grandma 2 Dad Sister 2 Aunt 2 Grandpa 2 Uncle 2 Cousin 2 Aunt 3
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
What is / are the possible genotype(s) of Grandma 1, Grandpa 1, Grandma 2, Grandpa 2.

Transcribed Image Text:The image depicts a pedigree chart illustrating the inheritance pattern of albinism within a family. This genetic condition is represented by the presence of the albino allele (a), while the normal allele is denoted by (A).
### Key Symbols:
- **Circle**: Female individual.
- **Square**: Male individual.
- **Shaded (Black) Symbol**: Individual affected by albinism.
- **Unshaded (White) Symbol**: Unaffected individual.
### Generational Breakdown:
1. **First Generation:**
- **Grandma 1** (unaffected female) and **Grandpa 1** (affected male).
- **Grandma 2** (unaffected female) and **Grandpa 2** (unaffected male).
2. **Second Generation:**
- **Aunt 1** (unaffected female), **Mom** (unaffected female), and **Uncle 1** (unaffected male) are offspring of Grandma 1 and Grandpa 1.
- **Dad** (unaffected male), **Aunt 2** (unaffected female), **Uncle 2** (affected male), and **Aunt 3** (unaffected female) are offspring of Grandma 2 and Grandpa 2.
3. **Third Generation:**
- **Cousin 1** (affected female) is the child of Uncle 1 and an unknown partner.
- **Sister 1** (unaffected female), **Affected Individual** (affected male), and **Sister 2** (affected female) are children of Mom and Dad.
- **Cousin 2** (unaffected male) is the child of Aunt 3 and an unknown partner.
### Pedigree Analysis:
- The chart showcases autosomal recessive inheritance, where individuals with two albino alleles (aa) are affected.
- Parents who have a normal phenotype but carry one albino allele each can have affected offspring. This is observed in the third generation with the affected individual and affected siblings.
This pedigree helps illustrate the genetic transmission of albinism and the recessive nature of the condition.
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Follow-up Question
What is the possible genotype(s) of Uncle 1, Uncle 2, Cousin 1, Cousin 2, Sister 1, Sister 2

Transcribed Image Text:### Genetic Pedigree Chart Analysis
This pedigree chart illustrates the inheritance pattern of an autosomal recessive trait—specifically, albinism—within a family. The chart is a visual tool used to track the inheritance of genetic traits across multiple generations.
#### Key:
- **A** = normal allele
- **a** = albino allele
- **Squares** represent males.
- **Circles** represent females.
- **Shaded symbols** indicate individuals expressing albinism (aa genotype).
- **Unshaded symbols** indicate individuals who either carry the normal allele or are carriers of the albino allele (AA or Aa genotype).
#### Generations and Individuals:
- **Generation I:**
- **Grandma 1 and Grandpa 1:** Grandma 1 is unshaded (carrier or non-carrier), and Grandpa 1 is shaded (affected).
- **Grandma 2 and Grandpa 2:** Both unshaded, carriers or non-carriers.
- **Generation II:**
- **Uncle 1, Aunt 1, and Mom:** All unshaded, carrying at least one normal allele.
- **Dad:** Unshaded, carrying at least one normal allele.
- **Aunt 2 and Aunt 3:** Unshaded, carriers or non-carriers.
- **Uncle 2:** Shaded, indicating he is affected.
- **Generation III:**
- **Cousin 1:** Shaded, indicating affected status.
- **Sister 1:** Unshaded, carrier or non-carrier.
- **Affected Individual:** Shaded, indicating affected status.
- **Sister 2:** Shaded, indicating affected status.
- **Cousin 2:** Unshaded, carrier or non-carrier.
This chart helps illustrate the manner in which the recessive albino allele is passed down through the family. Affected individuals must inherit the albino allele from both parents, mainly appearing when two carriers have children.
Solution
Follow-up Question
What is / are the possible genotype(s) of Aunt 1, Aunt 2, Aunt 3, MoM, Dad ,
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