The first reaction in Glycolysis is the phosphorylation of Glucose: Pi + Glucose → Glucose 6-Phosphate + water This is a thermodynamically unfavorable process with a ∆G0’ = +13.8 kJ/mol.  In a liver cell at 370C the concentrations of both phosphate and glucose are normally maintained at about 0.005 M each.  What would be the equilibrium concentration of Glucose 6-Phosphate according to the above data?  Note:  In the biochemical standard state ​[H2O] = 1.0 (this will help with the question below) When the reaction described in question number 3 is coupled to the hydrolysis of ATP the equilibrium concentration of Glucose 6-Phosphate goes to: a. 10.5 b. 350 c. 3000 d. 77 e. 4.5 f. 55 g. 550 h. 652 i. 1120

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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The first reaction in Glycolysis is the phosphorylation of Glucose:
Pi + Glucose → Glucose 6-Phosphate + water
This is a thermodynamically unfavorable process with a ∆G0’ = +13.8 kJ/mol.  In a liver cell at
370C the concentrations of both phosphate and glucose are normally maintained at about 0.005 M each.  What would be the equilibrium concentration of Glucose 6-Phosphate according to the above data?  Note:  In the biochemical standard state ​[H2O] = 1.0 (this will help with the question below)

When the reaction described in question number 3 is coupled to the hydrolysis of ATP the equilibrium concentration of Glucose 6-Phosphate goes to:

a. 10.5

b. 350

c. 3000

d. 77

e. 4.5

f. 55

g. 550

h. 652

i. 1120

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