The epinephrine signaling pathway plays a role in regulating glucose homeostasis in muscle cells. The signaling pathway is activated by the binding of epinephrine to the beta-2 adrenergic receptor. A simplified model of the epinephrine signaling pathway is represented in Figure 1. Epinephrine Plasma Membrane Beta-2 Adrenergic Receptor GDP GDP G Protein GTP GTP Adenylyl Cyclase ATP Cyclic AMP Protein Kinase A -ATP ADP Phosphorylase Kinase -ATP ADP Glycogen Phosphorylase Glycogen Glucose-1-Phosphate Figure 1. A simplified model of the epinephrine signaling pathway in muscle cells Which of the following is true? O G protein binding causes a shape change in adenylyl cyclase O epinephrin binding will not result in G protein activation O GDP displaces GTP on the G protein when activated O phosphorylase kinase will not become phosphorylated Glycolysis
The epinephrine signaling pathway plays a role in regulating glucose homeostasis in muscle cells. The signaling pathway is activated by the binding of epinephrine to the beta-2 adrenergic receptor. A simplified model of the epinephrine signaling pathway is represented in Figure 1. Epinephrine Plasma Membrane Beta-2 Adrenergic Receptor GDP GDP G Protein GTP GTP Adenylyl Cyclase ATP Cyclic AMP Protein Kinase A -ATP ADP Phosphorylase Kinase -ATP ADP Glycogen Phosphorylase Glycogen Glucose-1-Phosphate Figure 1. A simplified model of the epinephrine signaling pathway in muscle cells Which of the following is true? O G protein binding causes a shape change in adenylyl cyclase O epinephrin binding will not result in G protein activation O GDP displaces GTP on the G protein when activated O phosphorylase kinase will not become phosphorylated Glycolysis
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:The epinephrine signaling pathway plays a role in regulating glucose homeostasis in muscle cells. The signaling pathway is activated by the binding of
epinephrine to the beta-2 adrenergic receptor. A simplified model of the epinephrine signaling pathway is represented in Figure 1.
Epinephrine
Plasma
Membrane
Beta-2
Adrenergic
Receptor
GTP
(GDP GTP
(GDP) G Protein
Adenylyl
Cyclase
ATP
Cyclic AMP
Protein Kinase A
-ATP
ADP
Phosphorylase Kinase
-ATP
ADP
Glycogen Phosphorylase
Glycogen
Glucose-1-Phosphate
Figure 1. A simplified model of the epinephrine signaling pathway in muscle cells
Which of the following is true?
G protein binding causes a shape change in adenylyl cyclase
epinephrin binding will not result in G protein activation
GDP displaces GTP on the G protein when activated
O phosphorylase kinase will not become phosphorylated
Glycolysis

Transcribed Image Text:The epinephrine signaling pathway plays a role in regulating glucose homeostasis in muscle cells. The signaling pathway is activated by the binding of
epinephrine to the beta-2 adrenergic receptor. A simplified model of the epinephrine signaling pathway is represented in Figure 1.
Epinephrine
Plasma
Membrane
Beta-2
Adrenergic
Receptor
(GDP
(GDP G Protein
GTP
GTP
Adenylyl
Cyclase
O It breaks down glycogen
O it inhibits the glycolysis process
it binds to adenylyl cyclase
It phosphorylates phosphorylase kinase
It is inhibited by Cyclic AMP
ATP
Cyclic AMP
Protein Kinase A
-ATP
ADP
Phosphorylase Kinase
-ATP
ADP
Glycogen Phosphorylase
Glycogen
Glucose-1-Phosphate
Figure 1. A simplified model of the epinephrine signaling pathway in muscle cells
Which is true of Protein Kinase A?
Glycolysis
Expert Solution

Step 1
*Cell signaling also called as cell communication, is the ability of a cell to receive and process and transmit signals with its environment as well as with itself.
* Signals from outside a cell can be physical agents such as mechanical pressure and voltage and temperature and light and chemical signals
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