The enzyme Malate Dehydrogenase (MD) catalyzes the conversion of malate to oxaloacetate using nicotinamide adenine dinucleotide (NAD) as an enzyme cofactor (or coenzyme). Answer the following questions about this reaction. See pp. 462-467 of your textbook for further information.(a) Briefly explain how we know that this reaction (malate → oxaloacetate) is an oxidation-reduction reaction.(b) Write out the two reductive half reactions and indicate the ε°' for each half reaction. Write out the full balanced reaction for the malate to oxaloacetate reaction and indicate the Δε°' for the reaction.(c) What is the free energy change under standard state conditions (ΔG°') for this reaction? Which direction is spontaneous?

Malate dehydrogenase (MDH) catalyzes the interconversion between malate and oxaloacetate which is a…

Answered: The enzyme Malate Dehydrogenase (MD)…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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