This is a depiction of the connection between the urea cycle, the malate-aspartate shuttle, and the citric acid cycle. In this depiction, blank boxes with numbers are hiding the name of a metabolite. Using the list below the pathway name the missing metabolites.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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This is a depiction of the connection between the urea cycle, the malate-aspartate shuttle, and the citric acid cycle. In this depiction, blank boxes with numbers are hiding the name of a metabolite. Using the list below the pathway name the missing metabolites. Hint: Start by identifying #1, #6, and #7 and work from there.
8.
6.
7.
9.
NADH
NAD+
#
Glutamate
a-ketoglutarate
a-ketoglutarate
Glutamate
NADH
NAD+
7.
10.
Cytosol
Fumarate
2.
Citrulline
Oxaloacetate
3.
Citrulline
6.
1.
Mitochondrial
matrix
5.
4.
1.
Metabolite name:
2. Metabolite name (this metabolite breaks down into #3 and #8):
3. Metabolite name:
4. Metabolite name:
5. Metabolite name:
Metabolite name (this is the same metabolite as #5):
Metabolite name (this same metabolite is moved to the cytosol can combine with citrulline to make
#2 OR can be transaminated to make #9):
8. Metabolite name:
9. Metabolite name:
10. Metabolite name:
Transcribed Image Text:8. 6. 7. 9. NADH NAD+ # Glutamate a-ketoglutarate a-ketoglutarate Glutamate NADH NAD+ 7. 10. Cytosol Fumarate 2. Citrulline Oxaloacetate 3. Citrulline 6. 1. Mitochondrial matrix 5. 4. 1. Metabolite name: 2. Metabolite name (this metabolite breaks down into #3 and #8): 3. Metabolite name: 4. Metabolite name: 5. Metabolite name: Metabolite name (this is the same metabolite as #5): Metabolite name (this same metabolite is moved to the cytosol can combine with citrulline to make #2 OR can be transaminated to make #9): 8. Metabolite name: 9. Metabolite name: 10. Metabolite name:
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