The Drosophila fruit fly genes ebony (e) and claret (ca) are linked on chromosome 3. In Drosophila, wild-type alleles are indicated with a + and mutant allele without, as in e' and e. Draw all the possible allele arrangements for a fly that is heterozygous for both genes.
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- 3. The allele b gives Drosophila flies a black body and b+ gives brown, the wild-type phenotype. The allele wx of a separate gene gives waxy wings and wx+ gives nonwaxy, the wild-type phenotype. The allele cn of a third gene gives cinnabar eyes and cn+ gives red, the wild-type phenotype. A female heterozygous for these three genes is testcrossed, and 1000 progeny are classified as follows: 5 wild type; 6 black, waxy, cinnabar; 69 waxy, cinnabar; 67 black; 382 cinnabar; 379 black, waxy; 48 waxy; and 44 black, cinnabar. Are these three genes linked? If so, draw a map of the chromosomes in the heterozygous parent, showing the order, arrangement, and map distance between the linked genes.0. In Drosophila, the gene for cinnabar eye color is onchromosome 2, and the gene for scarlet eye color is onchromosome 3. A fly homozygous for both recessivecinnabar and scarlet alleles (cn/cn; st/st) is white-eyed.a. If male flies (containing chromosomes with thenormal gene order) heterozygous for cn and st allelesare crossed to white-eyed females homozygous forthe cn and st alleles, what are the expected phenotypes and their frequencies in the progeny?b. One unusual male heterozygous for cn and st alleles,when crossed to a white-eyed female, produced onlywild-type and white-eyed progeny. Explain the likelychromosomal constitution of this male.c. When the wild-type F1 females from the cross withthe unusual male were backcrossed to normal cn/cn;st/st males, the following results were obtained:wild type 45%cinnabar 5%scarlet 5%white 45%Diagram a genetic event at metaphase I that couldproduce the rare cinnabar or scarlet flies among theprogeny of the wild-type F1 females.1. The allele G for yellow stigma is completely dominant to green (g). Supposingtwo strains of autotetraploid plants are available and their genotypes are as follows:GGgg – in this plant the gene is close to the centromereGggg – in this plant the gene is far from the centromere If these two plants are crossed:a) provide the gametes that can be obtained from the two plants;b) provide the genotypic and phenotypic ratios of the offspring. 2. Consider the illustration below. Diagram the configuration you would observe at Anaphase I if crossing-over happens within the inversion. (IMAGE ATTACHED)
- 1.In Drosophila melanogaster body color is controlled by one gene while wing shape is controlled by a second gene. Gray body color is dominant to black body color, and normal wings are dominant to vestigial wings. Flies homozygous for gray body color and vestigial wings are crossed with flies homozygous for black body color and normal wings. A.compare the possible f2 generation genotypes and phenotypes and proportions if these two traits. B.How does your answer change if one of the original parents is homozygous for gray body color and normal wings while the other has black body color and vestigial wings?4. In Drosophila melanogaster the wild-type eye çolour is dark red. A pure-breeding mutant strain with brown eyes also exists. When brown-eyed flies are crossed to wild-type flies all of the Fi progeny are dark red-eyed. F1 flies were intercrossed and the F2 analvsed. In a total of 200 F2 flies there were 141 wild- type flies and 59 brown-eyed flies. There was no difference in the result between male and female F2 progeny. Some F1 flies were test crossed to brown-eyed flies and of 88 progeny, 48 were wild- type and 40 were brown-eyed with no differences between the sexes. - Interpret these results as fully as possible. b) A cross between two wild-type flies gave progeny all of which were wild type. When they were test crossed to flies the following results were obtained: vg e i) % of the test crosses gave wild type, westigal ebony, vestigal and ebony in a 1:1:1:1 ratio. ii) 4 of the test crosses gave all wild type. iii) % of the test crosses gave yestigal and wild type in a 1:1 ratio.…4. In Drosophila, three autosomal, recessive mutations are ebony body (e), sepia eye color (s), and hairless bristles (h). A female fly heterozygous at all loci was testcrossed with an ebony, sepia, hairless male; the progeny are shown below. Using the gene symbols stated åbove, answer the following questions. Phenotype Observed # of offspring Ebony sepia, hairless ebony, sepia 57 53 344 346 ral Hairless ebony, hairless Sepia wild type ebony, sepia, hairless Total offspring 11 9. 89 91 1000 A. Give the genotypes of the flies in the testcross. Write the answer using the gene symbols stated above and using proper notation. B. Deduce the linkage map showing all distances among the three genes. C. Calculate the interference. Show all work.
- 4. In Drosophila melanogaster, a yellow-bodied (dark coloured) male with vestigial (underformed) wings is crossed to a wildtype female (brown body, red eyes). The F1 generation are all wildtypes. An F1 male and female are crossed and the F2 progeny consists of 16 vestigial-winged males with yellow bodies, 48 yellow males with normal wings, 15 males with vestigial wings and yellow bodies, 49 wildtype males, 31 vestigial winged females with brown bodies and 97 wildtype females. Explain the inheritance pattern of the 2 genes.6. In Drosophila melanogaster, the wild-type eye colour is dark red. A pure-breeding mutant strain with white eyes also exists. When reciprocal crosses are made between (i) a white-eyed male a wild-type female, and (ii) a white-eyed female a wild-type male, the progeny are as follows: (1) P: White-eyed male x red-eyed female F1: red-eyed males and females F2: 100 progeny; 27 red-eved males, 24 white-eyed males, 49 red-eyed females (ii) P: red eyed male x white-eyed female F1: white-eyed males and red-eyed females F2: 100 progeny; 23 red-eved males 26 white-eyed males, 28 red-eyed females, 23 white-eyed females. How do you interpret these data?3. Two Drosophila flies that had normal (transparent, long) wings were mated. In the progeny, two new phenotypes appeared, dusky wings (having a semi-opaque appearance) and clipped wings (with squared ends). The progeny were as follows: Females: Males: 179 transparent, long 58 transparent, clipped 92 transparent, long 89 dusky, long 28 transparent, clipped 31 dusky, clipped a) Provide a genetic explanation for these results, showing genotypes of parents and of all progeny classes under your model. b) Design a test for your model.
- 6. In Drosophila, Bar eyes (B) is dominant trait located on the X chromosome, apterous wings (ap) are a recessive trait located on chromosome 2, and ebony body color (e) is a recessive trait located on chromosome 3. A homozygous Bar eyed, apterous female is mated to a homozygous ebony male. The F1 flies are crossed. In the F2 generation, at what frequency will Bar eyed, apterous, and ebony males be observed? а. 3/64 b. 1/64 с. О d. 9/64 е. 1/32 f. 3/322. a. A Drosophila male from a true-breeding stockwith scabrous eyes was mated with a female from atrue-breeding stock with javelin bristles. Both scabrous eyes and javelin bristles are autosomal recessive mutant traits. The F1 progeny all had normaleyes and bristles. F1 females from this cross weremated with males with both scabrous eyes andjavelin bristles. Write all the possible phenotypicclasses of the progeny that could be produced from the cross of the F1 females with the scabrous, javelin males, and indicate for each class whether it is arecombinant or parental type.b. The cross in part (a) yielded the following progeny:77 scabrous eyes and normal bristles; 76 wild type(normal eyes and bristles); 74 normal eyes andjavelin bristles; and 73 scabrous eyes and javelinbristles. Are the genes governing these traits likelyto be linked, or do they instead assort independently? Why?c. Suppose you mated the F1 females from the crossin part (a) to wild-type males. Why would thiscross fail…166. In Drosophila crossing over occurs in female but not in male. Gene A and B are 10 map unit apart on chromosome. A female Drosophila with genotype AB/ab and male Drosophila with genotype AB/ab. How many type of gametes are produced by female and male Drosophila respectively (1) 4 types : 2 types (2) 2 types : 2 types (3) 4 types : 4 types (4) 4 types : one types