The action potential generated in the squid giant axon requires voltage-gated potassium channels. Describe the shape of the action potential if these channels are blocked using TEA (Tetraethylammonium).
Enzyme kinetics
In biochemistry, enzymes are proteins that act as biological catalysts. Catalysis is the addition of a catalyst to a chemical reaction to speed up the pace of the reaction. Catalysis can be categorized as either homogeneous or heterogeneous, depending on whether the catalysts are distributed in the same phase as that of the reactants. Enzymes are an essential part of the cell because, without them, many organic processes would slow down and thus will affect the processes that are important for cell survival and sustenance.
Regulation of Enzymes
A substance that acts as a catalyst to regulate the reaction rate in the living organism's metabolic pathways without itself getting altered is an enzyme. Most of the biological reactions and metabolic pathways in the living systems are carried out by enzymes. They are specific for their works and work in particular conditions. It maintains the best possible rate of reaction in the most stable state. The enzymes have distinct properties as they can proceed with the reaction in any direction, their particular binding sites, pH specificity, temperature specificity required in very few amounts.
* Voltage gated potassium channels are transmembrane proteins that opens in response to depolarization of membrane.
* In excitable cells they help in repolarizing the membrane to its resting voltage after an action potential.
*Tetraethylammonium (TEA+) is a small organic cation that blocks K+ channels.
*In squid axons, TEA+ blocks from inside. TEA+, unlike K+, cannot pass through a narrower part of pore so it blocks rather than permeating.
* Once the potassium channels opens to voltage step they remain open.
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