Tab. 6. Mechanisms of intracellular accumulation of substances (Intracellular Accumulations or parenchymal dystrophies) 1. Normal cell 13 Protein mutation 0 Complex Soluble substrate products Enzyme (1) Abnormal metabolism. 2 Defect in protein folding, transport -X- 3 Lack of enzyme Fatty liver 4 Ingestion of indigestible materials CH Accumulation of abnormal proteins Complex substrate Lysosomal storage disease accumulation of endogenous materials Accumulation of exogenous materials 2. 3. 4.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Tab. 6. Mechanisms of intracellular accumulation of substances (Intracellular Accumulations or parenchymal dystrophies)
1.
Normal cell
Protein mutation
Complex
substrate
Soluble
products
Enzyme
Abnormal
metabolism
Defect in
protein
folding,
transport
-X->
Lack of
enzyme
Fatty liver
4
Ingestion of
indigestible
materials
Accumulation of
abnormal proteins
Complex
substrate
Lysosomal storage disease:
accumulation of
endogenous materials
Accumulation of
exogenous materials
12.
3.
4.
Transcribed Image Text:Tab. 6. Mechanisms of intracellular accumulation of substances (Intracellular Accumulations or parenchymal dystrophies) 1. Normal cell Protein mutation Complex substrate Soluble products Enzyme Abnormal metabolism Defect in protein folding, transport -X-> Lack of enzyme Fatty liver 4 Ingestion of indigestible materials Accumulation of abnormal proteins Complex substrate Lysosomal storage disease: accumulation of endogenous materials Accumulation of exogenous materials 12. 3. 4.
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