the protein you are making is one that is not destined to be secreted into the extracellular space, but instead is meant to function within the cytoplasm. How will the synthesis of these types of protein be different? Why?
Proteins
We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.
Protein Expression
The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.
Now assume that the protein you are making is one that is not destined to be secreted into the extracellular space, but instead is meant to function within the cytoplasm. How will the synthesis of these types of protein be different? Why?
![NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE
Organelles in Concert:
Modeling the Coordination of Cell Structures
by
Alexandra V. Tremblay
Department of Biology
University of North Georgia, Dahlonega, GA
Sonic Hedgehog Protein Synthesis
After completing this activity, you should be able to describe the function(s) and spatial arrangement of each organelle within the
cell and be able to describe the coordination among the organelles necessary for cellular function.
Background:
Sonic Hedgehog protein (SHH) is an essential 462 amino acid protein produced in vertebrates during the early stages of
embryonic development [1]. The protein is encoded by the shh gene, which in humans is located on chromosome 7 [2]. The SHH
protein that is produced by this gene is called a "morphogen," or chemical agent that drives morphological changes in an
organism. After synthesis, a cholesterol molecule is added to the C-terminal end of the amino acid sequence, and SHH is
secreted by the cell into the extracellular space [3]. Once SHH is outside the cell, it forms a concentration gradient that promotes
the development of several types of specialized tissue including the brain, spinal cord, and limbs and digits in vertebrates [4].](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F8bce45ac-d4bb-4c39-ab64-6aff595f666a%2Fe49f9ea4-81ab-4345-a8d0-8850194f97b5%2F3d74zm_processed.png&w=3840&q=75)
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
