Suppose you are planning the separation of three compounds (A, B, and C) by column chromatography (CC) on silica gel. You start by running several TLC’s in order to find the best solvent system for the separation. The results are summarized in the table below. Which solvent or solvents would be best for a separation of compound C (from A and B) by column chromatography? Solvent Rf for A Rf for B Rf for C Hexane 0.04 0.30 0.04 Toluene 0.22 0.45 0.19 Dichloromethane 0.52 0.75 0.45 Ethyl acetate 0.80 0.80 0.76
Suppose you are planning the separation of three compounds (A, B, and C) by column chromatography (CC) on silica gel. You start by running several TLC’s in order to find the best solvent system for the separation. The results are summarized in the table below. Which solvent or solvents would be best for a separation of compound C (from A and B) by column chromatography? Solvent Rf for A Rf for B Rf for C Hexane 0.04 0.30 0.04 Toluene 0.22 0.45 0.19 Dichloromethane 0.52 0.75 0.45 Ethyl acetate 0.80 0.80 0.76
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Suppose you are planning the separation of three compounds (A, B, and C) by column chromatography (CC) on silica gel. You start by running several TLC’s in order to find the best solvent system for the separation. The results are summarized in the table below. Which solvent or solvents would be best for a separation of compound C (from A and B) by column chromatography?
|
Solvent |
Rf for A |
Rf for B |
Rf for C |
|
Hexane |
0.04 |
0.30 |
0.04 |
|
Toluene |
0.22 |
0.45 |
0.19 |
|
Dichloromethane |
0.52 |
0.75 |
0.45 |
|
Ethyl acetate |
0.80 |
0.80 |
0.76 |
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