Suppose your TLC plate looks like the image below (ran 1:1 ratio ethyl acetate/hexane). What is the Rf value of the red compound (lower compound, 1 cm from the baseline)? How could the solvent combination be varied to lower the Rf value of the red product? How can we change the eluent composition to improve the separation of the two products on column chromatography? Solvent line 6.8 cm 5.1 cm X--X-- Base line SM Co P rf value choices: 0.1, 0.15, 0.25, 0.3, 0.35, 1.15 how could solvent combination be varied choices: increase ratio of hexane or decrease ratio of hexane how can we change eluent composition choices: start with more polar eluent or start with less polar eluent

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Chapter1: Chemical Foundations
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Suppose your TLC plate looks like the image below (ran 1:1 ratio ethyl acetate/hexane).
What is the Rf value of the red compound (lower compound, 1 cm from the baseline)?
How could the solvent combination be varied to lower the Rf value of the red product?
How can we change the eluent composition to improve the separation of the two products on column chromatography?
Solvent line
6.8 cm
5.1 cm
-* --X- -× -
Base line
SM Co P
rf value choices: 0.1, 0.15, 0.25, 0.3, 0.35, 1.15
how could solvent combination be varied choices: increase ratio of hexane or decrease ratio of hexane
how can we change eluent composition choices: start with more polar eluent or start with less polar eluent
Transcribed Image Text:Suppose your TLC plate looks like the image below (ran 1:1 ratio ethyl acetate/hexane). What is the Rf value of the red compound (lower compound, 1 cm from the baseline)? How could the solvent combination be varied to lower the Rf value of the red product? How can we change the eluent composition to improve the separation of the two products on column chromatography? Solvent line 6.8 cm 5.1 cm -* --X- -× - Base line SM Co P rf value choices: 0.1, 0.15, 0.25, 0.3, 0.35, 1.15 how could solvent combination be varied choices: increase ratio of hexane or decrease ratio of hexane how can we change eluent composition choices: start with more polar eluent or start with less polar eluent
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