Suppose a maternal effect gene exists as a functional dominant allele and a nonfunctional recessive allele. A mother with the disorder produces all offspring without the disorder. Explain the genotype of the mother.
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Suppose a maternal effect gene exists as a functional dominant allele and a nonfunctional recessive allele. A mother with the disorder produces all offspring without the disorder. Explain the genotype of the mother.
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- Suppose a maternal effect gene exists as a functional dominantallele and a nonfunctional recessive allele. A mother who is phenotypically abnormal produces all normal offspring. Explain thegenotype of the motherSuppose a maternal effect gene exists as a functional dominantallele and a nonfunctional recessive allele that causes a disorder.A mother with the disorder produces offspring that are all withoutthe disorder. Explain the genotype of the mother.In man, muscular dystrophy is a condition in which the muscles waste away during early life and may result in a shorter life expectancy. It is due to a sex-linked, recessive gene. A certain couple has five children – three boys (ages 1yr, 3yrs, and 10yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of this disease. You are their family physician and they come to you for advice. What would you tell them about the chances of their other children developing the disease?
- Explain the central dogma of inheritance. Cite a specific example.In the following pedigree, is the disorder’s mode of inheritanceautosomal dominant, autosomal recessive, or X-linked recessive?Explain your reasoning.If a gene is X-linked, explain why the recessive phenotype would be more often seen in males then in females. Also explain what the term “carrier” means related to these traits.
- Analysis of X-Linked Dominant and Recessive Traits A young boy is color-blind. His one brother and five sisters are not. The boy has three maternal uncles and four maternal aunts. None of his uncles children or grandchildren is color-blind. One of the maternal aunts married a color-blind man, and half of her children, both male and female, are color-blind. The other aunts married men who have normal color vision. All their daughters have normal vision, but half of their sons are color-blind. a. Which of the boys four grandparents transmitted the gene for color blindness? b. Are any of the boys aunts or uncles color-blind? c. Is either of the boys parents color-blind?Analysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic disorder in a family, you are able to collect a four-generation pedigree that details the inheritance of the disorder in question. Analyze the information in the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linkedRegarding Mendelian inheritance in diploid individuals, (Read each statement carefully. Select all of the statements below that are true (that you agree with). Leave any statements that are false (that you do not agree with) un- selected.) a diploid individual receives two copies of every autosome from the previous generation. for every autosomal gene inherited by an individual, both copies can come from one parent. a diploid individual gives two copies of every autosome to a child in the next generation. to be diploid means that two independent genes are specified in the individual's genotype.
- An individual with 46, XX genotype is diagnosed with Duchenne-type Muscular Dystrophy, a recessive X-linked disorder. Genetic tests confirm that this individual is a heterozygote for this disorder. Briefly, but specifically, explain how it’s possible that they are showing symptoms of this disorder.Explain why disease alleles for cystic fibrosis (CF)are recessive to the normal alleles (CF+), yet thedisease alleles responsible for Huntington disease(HD) are dominant to the normal alleles (HD+).X‑linked, recessive diseases, such as hemophilia, are extremely rare in the population. However, many women are carriers and show no sign of the disease. The pedigree illustrates the inheritance of an X‑linked, recessive disease. Determine whether the unknown individuals are affected by the disease, unaffected by the disease, or carriers of the X‑linked recessive allele. Unaffected individuals are not carriers of the X‑linked recessive allele.
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