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You are presented with the following clinical scenario: "A 12 month old male child presents with recurrent bacterial infections. Flow cytometry shows a complete lack of B- lymphocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis O HIV/AIDS O COVID-19 O LAD type 1 CD4-FITC CD8-PE CD45-PE CD8-PE 70% 13% 52% 10% 82% 27% 5% CD8-PE CD4-FITC CD20-FITC CD4-FITC 17% 38% 13% 68% Agammaglobulinaemia CD45-PE CD4-FITC CD45-PE CD45-PE 35% 8% 93% 22% CD15-FITC CD8-PE CD20-FITC CD15-FITC Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample 30% 0% 77%

You are presented with the following clinical scenario: "A 12 month old male child presents with recurrent bacterial infections. Flow cytometry shows a complete lack of B- lymphocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis O HIV/AIDS O COVID-19 O LAD type 1 CD4-FITC CD8-PE CD45-PE CD8-PE 70% 13% 52% 10% 82% 27% 5% CD8-PE CD4-FITC CD20-FITC CD4-FITC 17% 38% 13% 68% Agammaglobulinaemia CD45-PE CD4-FITC CD45-PE CD45-PE 35% 8% 93% 22% CD15-FITC CD8-PE CD20-FITC CD15-FITC Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample 30% 0% 77%

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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You are presented with the following clinical scenario: "A 12 month old male child presents with recurrent bacterial infections. Flow cytometry shows a complete lack of B- lymphocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis O HIV/AIDS O COVID-19 O LAD type 1 U E CD4-FITC CD8-PE CD45-PE CD8-PE 70% 13% 52% 10% 82% 5% 27% 5% CD8-PE CD4-FITC CD20-FITC CD4-FITC 17% 38% 13% 68% Agammaglobulinaemia CD45-PE CD4-FITC CD45-PE CD45-PE 35% 3% 62% 8% 93% 22% CD15-FITC CD8-PE CD20-FITC CD15-FITC Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample 62% 30% 0% 77%
Transcribed Image Text:You are presented with the following clinical scenario: "A 12 month old male child presents with recurrent bacterial infections. Flow cytometry shows a complete lack of B- lymphocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis O HIV/AIDS O COVID-19 O LAD type 1 U E CD4-FITC CD8-PE CD45-PE CD8-PE 70% 13% 52% 10% 82% 5% 27% 5% CD8-PE CD4-FITC CD20-FITC CD4-FITC 17% 38% 13% 68% Agammaglobulinaemia CD45-PE CD4-FITC CD45-PE CD45-PE 35% 3% 62% 8% 93% 22% CD15-FITC CD8-PE CD20-FITC CD15-FITC Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample 62% 30% 0% 77%
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So would it be HIV/AIDS instead of Agammaglobulinaemia?

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