Mike, an unvaccinated university student traveled to Western Europe, where he contracted mumps (viral infection). A month after his return, his roommate, Josh, also complained of symptoms of mumps. However, Josh had received his MMR vaccination as part of his childhood immunizations. IgM antibodies were detected in Mike’s serological test but not in Josh’s bloodwork. However, circulating IgG was detected in both patients. * IgM antibodies have a short half-life. IgG have a longer half-life (remain in an “active state” for longer, not broken down as quickly). Why was it significant that Mike had not been vaccinated and had traveled to Western Europe? What is the significance of finding Ig M antibodies? Why might Josh’s serology test results have been negative for mumps IgM and positive for IgG? Is it possible for Josh to have a mumps infection, even if he had been vaccinated as a child?

Immunoglobulin is the term collectively used for antibodies, and antibodies are the antigen-binding…

Answered: Mike, an unvaccinated university…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Mike, an unvaccinated university student traveled to Western Europe, where he contracted mumps (viral infection). A month after his return, his roommate, Josh, also complained of symptoms of mumps. However, Josh had received his MMR vaccination as part of his childhood immunizations. IgM antibodies were detected in Mike’s serological test but not in Josh’s bloodwork. However, circulating IgG was detected in both patients.

* IgM antibodies have a short half-life. IgG have a longer half-life (remain in an “active state” for longer, not broken down as quickly).

Why was it significant that Mike had not been vaccinated and had traveled to Western Europe?

What is the significance of finding Ig M antibodies?

Why might Josh’s serology test results have been negative for mumps IgM and positive for IgG?

Is it possible for Josh to have a mumps infection, even if he had been vaccinated as a child?

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