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You are presented with the following clinical scenario: "A 50 year old patient presents with fatigue, night sweats and weight loss. Flow cytometry shows increased number of immature leukocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis Chronic O Sepsis leukaemia O A E G CD14-PE CD3-APC CD3-APC CD14-PE 20% 5% 15% 4% 29% 8% 42% 7% CD16-FITC CD15-FITC CD15-FITC CD16-FITC Chronic Myelomonocytic Leukaemia 25% 50% 81% 63% 17% 34% H CD8-PE CD3-APC CD3-APC CD8-PE 27% 5% 6% 2% 0.3% 99% O Severe Combined Immunodeficiency CD4-V500 CD45-PE CD45-PE CD4-V500 68% 22% 72% 50% 48% 0.1% 0.6%

You are presented with the following clinical scenario: "A 50 year old patient presents with fatigue, night sweats and weight loss. Flow cytometry shows increased number of immature leukocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis Chronic O Sepsis leukaemia O A E G CD14-PE CD3-APC CD3-APC CD14-PE 20% 5% 15% 4% 29% 8% 42% 7% CD16-FITC CD15-FITC CD15-FITC CD16-FITC Chronic Myelomonocytic Leukaemia 25% 50% 81% 63% 17% 34% H CD8-PE CD3-APC CD3-APC CD8-PE 27% 5% 6% 2% 0.3% 99% O Severe Combined Immunodeficiency CD4-V500 CD45-PE CD45-PE CD4-V500 68% 22% 72% 50% 48% 0.1% 0.6%

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample
Transcribed Image Text:Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample
You are presented with the following clinical scenario: "A 50 year old patient presents with fatigue, night sweats and weight loss. Flow cytometry shows increased numbers of immature leukocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis Chronic O Sepsis leukaemia O A E G CD14-PE CD3-APC CD3-APC CD14-PE 20% 5% 15% 4% 29% 8% 42% 7% CD16-FITC CD15-FITC CD15-FITC CD16-FITC Chronic Myelomonocytic Leukaemia 25% 50% 181% 63% 17% 34% CD8-PE CD3-APC CD3-APC CD8-PE 27% 5% 6% 2% 0.3% 99% Severe Combined Immunodeficiency CD4-V500 CD45-PE CD45-PE CD4-V500 68% 22% 72% 50% 48% 0.1% 0.6%
Transcribed Image Text:You are presented with the following clinical scenario: "A 50 year old patient presents with fatigue, night sweats and weight loss. Flow cytometry shows increased numbers of immature leukocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis Chronic O Sepsis leukaemia O A E G CD14-PE CD3-APC CD3-APC CD14-PE 20% 5% 15% 4% 29% 8% 42% 7% CD16-FITC CD15-FITC CD15-FITC CD16-FITC Chronic Myelomonocytic Leukaemia 25% 50% 181% 63% 17% 34% CD8-PE CD3-APC CD3-APC CD8-PE 27% 5% 6% 2% 0.3% 99% Severe Combined Immunodeficiency CD4-V500 CD45-PE CD45-PE CD4-V500 68% 22% 72% 50% 48% 0.1% 0.6%
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