Sketch the pH speciation diagram for asparagine for the range of 1 < pH < 12, annotate with the position of the two pKa values and label the appropriate curves with the chemical structures of the three forms of asparagine in the pH range stated.
Sketch the pH speciation diagram for asparagine for the range of 1 < pH < 12, annotate with the position of the two pKa values and label the appropriate curves with the chemical structures of the three forms of asparagine in the pH range stated.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question

Transcribed Image Text:The amino acid asparagine is shown below in its zwitterionic form. It possesses two Ka values:
Ka1 = 9.5 x 10-³ and Ka2 = 1.6 x 10-⁹.
ne
NH3
asparagine
(a) Sketch the pH speciation diagram for asparagine for the range of 1 < pH < 12, annotate
with the position of the two pKa values and label the appropriate curves with the
chemical structures of the three forms of asparagine in the pH range stated.
Fraction
1
0.9
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0
0
1
H₂N.
2
3
4
5
6
pH
7
00
8
9
10
11
12
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