Sickle-cell anemia is a hereditary chronic blood disease that is extremely severe when an individual carries two copies of the defective gene. It is particularly common in countries plagued by malaria, a parasitic infection transmitted by mosquitoes. A study in Africa tested 543 children for the sickle-cell gene and also for malaria. In Group 1 which consisted of 136 children with the sickle-cell gene, 36 children had severe malaria infections. Group 2 consisted of 407 children without the sickle-cell gene, and 152 of them had severe malaria infections. Conduct a test to determine if the proportion of severe malaria infections among children with the sickle-cell trait is different from that among children without. Test at 5% level of significance. Question: What is your p value and t statistic ?

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Sickle-cell anemia is a hereditary chronic blood disease that is extremely severe when an individual carries two copies of the defective gene. It is particularly common in countries plagued by malaria, a parasitic
infection transmitted by mosquitoes. A study in Africa tested 543 children for the sickle-cell gene and also for malaria. In Group 1 which consisted of 136 children with the sickle-cell gene, 36 children had severe malaria
infections. Group 2 consisted of 407 children without the sickle-cell gene, and 152 of them had severe malaria infections. Conduct a test to determine if the proportion of severe malaria infections among children with
the sickle-cell trait is different from that among children without. Test at 5% level of significance. Question: What is your p value and t statistic ? 

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