A View AssessmentAlthea Gem messaged youContentA adamson.blackboard.com/ultra/courses/_12158_1/outline/assessment/_1143292_1/overview/attempt/_3601644_1?courseld=_12158_1PausedCoExam ContentDetails & InformationQuestion 120 PointsAssessment due date9/20/21, 7:00 PM (UTC+8)X Time limit90 minutes | Automatic submissionRibosome-associatedchaperonesNative proteinsPolypeptide emergingfrom ribosome3StressAttempts1 attempt leftSpontaneous or chaperone-mediated protein folding:• Hsp70/Dnak• Hsp60/GroEL• Hsp90E Originality ReportSafeAssign enabledUnfolded, misfoldedand non-native proteinsGradingDelivery tocompartmentalizedproteases:• Clp/Hsp100Protection from aggregation:• sHsp• Hsp70/Dnak• Hsp90• Clp/Hsp100E Maximum pointsFool80 pointsDisaggregationand reactivation:• Cip/Hsp100 + Hsp70• Hsp90 + Hsp70Degraded proteinsProtein aggregatesExplain and discuss the diagram. (The Role of Chaperones in Protein Folding)*You can underline or make the keywords bold for emphasis.*You have to base your answers only from our lecture/discussion and not from other sources.Sample structure of essay:1st paragraph: Introduction and preliminary explanation of the diagram2nd paragraph: Follow-up and additional discussion.3rd paragraph: Final discussion and conclusion.PriO 90 minutes remainingSave and CloseSubmitTer5:42 PMP Type here to search28°CA O O ENG20/09/2021近

The three dimensional confirmation of protein is important for their biological function. Some…

Answered: Ribosome-associated chaperones Native…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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In the presence of cephalosphorin, what will be the protein product of the prokaryotic cell gene shown below? 5'-CATGTCAGTAAGGCATCT-3' (Assume this is a segment of a larger structural gene that will be translated into protein in its entirety.)
Degradation of cyclins is controlled by a) phosphorylation by ubiquitylation c) de phosphorylation dl transcription E All J the above
Drug 2-Lumacaftor (VX-809): In people with the most common CF mutation, F508del, a series of problems prevents the CFTR protein from folding into the correct shape and reaching its proper place on the cell surface. The cell recognizes the protein as abnormal and targets it for degradation before it makes it to the cell surface. In order to treat this problem, two drugs are required - an agent to get the protein to the surface and then Ivacaftor to open the channel and increase chloride transport. The drug Lumacaftor has been identified as a treatment to help with the trafficking of the protein to the cell surface. When Lumacaftor is added to Ivacaftor, the protein gets to the surface and also increases chloride transport by increasing channel opening time. For which class(es) of mutations would Lumacaftor be most effective?
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E channel Charged tRNA Anticodon for START Initiating factors Release factors m III III exit site for an uncharged stem of tRNA UAC located on tRNA's anticodon arm proteins that help mRNA bind to a small and large ribosomal subunit to start translation a tRNA that contains its appropriate amino acid attached to the acceptor arm bind to STOP codons and result in a hydrolysis reaction that creates a drop of water that halts translation

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