Establishment of Beginning of the lytic pathway the lysogenic state cro protein inhibits transcription from PL and PRM- cro protein also inhibits PR. but only after transcription of the 10, P, and O genes has occurred. cll activates transcription from Pand PRE- cll ll cro int xis cll N cl cго cllo P о int xis clll NV cl cro cll O P Q Pi PR PRE OR tRI OL Рем tr2 PR PRE OR tRI OL Рем t PL ti PL tp2 Maintenance of cl (the à repressor) inhibits the lysogenic state P and PR but activates PRM- -a repressor Activates PRM Expression of phage genes shown in tan in Figure 18.7 leads to the synthesis of new phages and bacterial cell lysis. Inhibits P Inhibits PR int xis cll NV c/ cro cll O P Q Pi PR PRE tr2 OL OR tRI PRM (a) Lysogenic cycle (b) Lytic cycle FIGURE 18.10 Phage 2 gene regulation during the lysogenic and lytic cycles. (a) Gene regulation pattern that leads to the lysogenic cycle. (b) Steps that lead to the lytic cycle.

Human Anatomy & Physiology (11th Edition)
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What is the function of PRM?

Establishment of
Beginning of
the lytic pathway
the lysogenic state
cro protein inhibits transcription from
PL and PRM- cro protein also inhibits
PR. but only after transcription of the
10, P, and O genes has occurred.
cll activates transcription from Pand PRE-
cll
ll
cro
int xis
cll N
cl
cго cllo P о
int xis
clll NV cl
cro cll O P Q
Pi
PR PRE
OR tRI
OL
Рем
tr2
PR PRE
OR tRI
OL
Рем
t PL
ti PL
tp2
Maintenance of
cl (the à repressor) inhibits
the lysogenic state P and PR but activates PRM-
-a repressor
Activates PRM
Expression of phage genes shown in tan in Figure 18.7 leads
to the synthesis of new phages and bacterial cell lysis.
Inhibits P
Inhibits PR
int xis
cll NV c/
cro cll O P Q
Pi
PR PRE
tr2
OL
OR tRI
PRM
(a) Lysogenic cycle
(b) Lytic cycle
FIGURE 18.10 Phage 2 gene regulation during the lysogenic and lytic cycles. (a) Gene regulation pattern that leads to the lysogenic cycle.
(b) Steps that lead to the lytic cycle.
Transcribed Image Text:Establishment of Beginning of the lytic pathway the lysogenic state cro protein inhibits transcription from PL and PRM- cro protein also inhibits PR. but only after transcription of the 10, P, and O genes has occurred. cll activates transcription from Pand PRE- cll ll cro int xis cll N cl cго cllo P о int xis clll NV cl cro cll O P Q Pi PR PRE OR tRI OL Рем tr2 PR PRE OR tRI OL Рем t PL ti PL tp2 Maintenance of cl (the à repressor) inhibits the lysogenic state P and PR but activates PRM- -a repressor Activates PRM Expression of phage genes shown in tan in Figure 18.7 leads to the synthesis of new phages and bacterial cell lysis. Inhibits P Inhibits PR int xis cll NV c/ cro cll O P Q Pi PR PRE tr2 OL OR tRI PRM (a) Lysogenic cycle (b) Lytic cycle FIGURE 18.10 Phage 2 gene regulation during the lysogenic and lytic cycles. (a) Gene regulation pattern that leads to the lysogenic cycle. (b) Steps that lead to the lytic cycle.
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