R3.21. Alternate day fasting A paper published in 2017 in JAMA Internal Medicine (jamanetwork.com/journals/ jamainternalmedicine/fullarticle/2623528) reported on a study of alternate-day fasting as a weight-loss method. One hundred obese persons were assigned at random to one of three groups: an alternate-day fasting group, a calorie restric- tive group, and a control. The alternate-day fasting group alternately consumed 25% of their usual caloric intake during lunch on fasting days and 125% on the alternating days. The calorie restrictive group consumed 75% of baseline energy over three meals each day. The control group ate as usual. The study reports that there was essentially no difference in weight loss between the alternate-day fasting group and the calorie-restricted group, both losing an average of 6.8% of their weight. From this description, identify: a) The participants. b) The treatments. c) The response. d) Was the study blinded? If not, should it have been blinded? e) The participants were not a random sample from the population. Is that a problem for this study?

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R3.21. Alternate day fasting A paper published in 2017 in
JAMA Internal Medicine (jamanetwork.com/journals/
jamainternalmedicine/fullarticle/2623528) reported on a
study of alternate-day fasting as a weight-loss method. One
hundred obese persons were assigned at random to one of
three groups: an alternate-day fasting group, a calorie restric-
tive group, and a control. The alternate-day fasting group
alternately consumed 25% of their usual caloric intake during
lunch on fasting days and 125% on the alternating days. The
calorie restrictive group consumed 75% of baseline energy
over three meals each day. The control group ate as usual.
The study reports that there was essentially no difference in
weight loss between the alternate-day fasting group and the
calorie-restricted group, both losing an average of 6.8% of
their weight. From this description, identify:
a) The participants.
b) The treatments.
c) The response.
d) Was the study blinded? If not, should it have been
blinded?
e) The participants were not a random sample from the
population. Is that a problem for this study?
Transcribed Image Text:R3.21. Alternate day fasting A paper published in 2017 in JAMA Internal Medicine (jamanetwork.com/journals/ jamainternalmedicine/fullarticle/2623528) reported on a study of alternate-day fasting as a weight-loss method. One hundred obese persons were assigned at random to one of three groups: an alternate-day fasting group, a calorie restric- tive group, and a control. The alternate-day fasting group alternately consumed 25% of their usual caloric intake during lunch on fasting days and 125% on the alternating days. The calorie restrictive group consumed 75% of baseline energy over three meals each day. The control group ate as usual. The study reports that there was essentially no difference in weight loss between the alternate-day fasting group and the calorie-restricted group, both losing an average of 6.8% of their weight. From this description, identify: a) The participants. b) The treatments. c) The response. d) Was the study blinded? If not, should it have been blinded? e) The participants were not a random sample from the population. Is that a problem for this study?
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