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Question 5 of 14 Identify a correct comparison between MHC class I and class II molecules. O MHC class I molecules present peptides generated by the destruction of intracellular cytosolic proteins, whereas class Il molecules present peptides derived through phagocytosis. O The structural features of the peptide-binding groove are provided by a and B chains for class I molecules and by a; and a subdomains for class Il molecules. O Both MHC class I and class II molecules are dissimilar in their three-dimensional structures but similar in composition and the types of peptides they can bind. O The peptide-binding groove of MHC class I molecules contains a single pocket for binding peptides, whereas the groove of class II molecules contains two pockets. Question 6 of 14 Identify the similarity between MHC class I and class II molecules. O Both molecules contain two transmembrane subunits each. O Both molecules possess promiscuous binding specificity. O Both molecules accommodate peptides containing 13 to 25 amino acids. O Both molecules contain peptide-binding grooves formed by the interface of the a and ẞ chains.

Question 5 of 14 Identify a correct comparison between MHC class I and class II molecules. O MHC class I molecules present peptides generated by the destruction of intracellular cytosolic proteins, whereas class Il molecules present peptides derived through phagocytosis. O The structural features of the peptide-binding groove are provided by a and B chains for class I molecules and by a; and a subdomains for class Il molecules. O Both MHC class I and class II molecules are dissimilar in their three-dimensional structures but similar in composition and the types of peptides they can bind. O The peptide-binding groove of MHC class I molecules contains a single pocket for binding peptides, whereas the groove of class II molecules contains two pockets. Question 6 of 14 Identify the similarity between MHC class I and class II molecules. O Both molecules contain two transmembrane subunits each. O Both molecules possess promiscuous binding specificity. O Both molecules accommodate peptides containing 13 to 25 amino acids. O Both molecules contain peptide-binding grooves formed by the interface of the a and ẞ chains.

Introduction to General, Organic and Biochemistry
Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter31: Immunochemistry
Section: Chapter Questions
Problem 31.70P
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Question 5 of 14 Identify a correct comparison between MHC class I and class II molecules. O MHC class I molecules present peptides generated by the destruction of intracellular cytosolic proteins, whereas class Il molecules present peptides derived through phagocytosis. O The structural features of the peptide-binding groove are provided by a and B chains for class I molecules and by a; and a subdomains for class Il molecules. O Both MHC class I and class II molecules are dissimilar in their three-dimensional structures but similar in composition and the types of peptides they can bind. O The peptide-binding groove of MHC class I molecules contains a single pocket for binding peptides, whereas the groove of class II molecules contains two pockets. Question 6 of 14 Identify the similarity between MHC class I and class II molecules. O Both molecules contain two transmembrane subunits each. O Both molecules possess promiscuous binding specificity. O Both molecules accommodate peptides containing 13 to 25 amino acids. O Both molecules contain peptide-binding grooves formed by the interface of the a and ẞ chains.
Transcribed Image Text:Question 5 of 14 Identify a correct comparison between MHC class I and class II molecules. O MHC class I molecules present peptides generated by the destruction of intracellular cytosolic proteins, whereas class Il molecules present peptides derived through phagocytosis. O The structural features of the peptide-binding groove are provided by a and B chains for class I molecules and by a; and a subdomains for class Il molecules. O Both MHC class I and class II molecules are dissimilar in their three-dimensional structures but similar in composition and the types of peptides they can bind. O The peptide-binding groove of MHC class I molecules contains a single pocket for binding peptides, whereas the groove of class II molecules contains two pockets. Question 6 of 14 Identify the similarity between MHC class I and class II molecules. O Both molecules contain two transmembrane subunits each. O Both molecules possess promiscuous binding specificity. O Both molecules accommodate peptides containing 13 to 25 amino acids. O Both molecules contain peptide-binding grooves formed by the interface of the a and ẞ chains.
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