QUESTION 46In eukaryotic mitochondrial chemiosmosis, a proton-motive force allows protons to move through ATP synthase which couples this movement withATP synthesis. The protons are moving fromO a. the mitochondrial intermembrane space to the matrix.O b. the outside of the cell to the cytosolO c. the mitochondrial matrix to the intermembrane spaceO d. the cytoplasm to the mitochondrial matrixO e. the cytoplasm to the mitochondrial intermembrane spaceClick Save and Submit to save and submit. Click Save All Answers to save all answers.2==F2320 F3$4%5FS.MacBook ProWER T^6F67Y11U

A molecular assembly in the inner mitochondrial mebrain carries out the synthesis of ATP. This enzyme complex was originally called the mitochondrial ATPase or F1F0 ATPase. Because it was discovered through its catalysis of the reverse reaction, the hydrolysis of ATP. ATP synthase, it's preferred name, emphasizes its actual role in the mitochondrion. It is also called as complex V. It was first suggested that electron transfer leads to the formation of a covalent high energy intermediate that source as a high phosphoryl transfer potential compound or to the formation of an activated protein conformation, which then drives ATP synthesis. The search for such intermediate for such decades proved fruitless.In 1961, Peter Mitchell proposed that electron transport and ATP synthesis are coupled by a proton gradient across the inner mitochondrial membrane rather than by a covalent high energy intermediate or an activated protein conformation. In his model, the transfer of electrons through the respiratory chain lead to the pumping of protons from the matrix to the cytosolic side of the in the mitochondrial membrane (intermembrane space) .The H+ concentration becomes lower in the matrix, electric field with the matrix side negative is generated. This gradient created a stored form of energy. Mitchells idea called the chemi osmotic hypothesis, was that this chemoosmotc gradient causes the protons to mov from the mitochondrial cytoplasmic side to the matrix , through ATP synthase . Thus the proton motive force drives the synthesis of ATP by ATP synthase. His highly innovative hypothesis that oxidation and phosphorylation are coupled by a proton gradient is now supported by a wealth of evidence. Indeed electron transport generates the proton gradient across the inner mitochondrial membrane. The pH outside is 1.4 units lower than inside PH. And the membrane potential is 0.14 V , the outside being positive. The calculated membrane potential corresponds to a free energy of 5.2 kilo calories per mole of protons.ANSWER Q) In eukaryotic mitochondrial chemiosmosis, a proton Motive force allows the protons to move through the ATP synthase which couples the movement with the synthesis of ATP. The protons are moving from? Option a) the mitochondrial intermembrane space to the matrix.