Question 23 2 pts As it turns out, arsenic is a competitive inhibitor of pyruvate dehydrogenase. Suppose you add arsenic to human muscle tissue in a laboratory. What results would you expect to observe? I. Decreased ability of the tissue to relax after contraction II. Increased concentration of ADP in the mitochondrial matrix III. Increased concentration of lactic acid in the cytosol IV. Increased concentration of NADH and FADH2 in the mitochondrial matrix I, II, and IV II, III, IV I and II I and IV I, II, and III

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Question 23
2 pts
As it turns out, arsenic is a competitive inhibitor of pyruvate dehydrogenase. Suppose you add
arsenic to human muscle tissue in a laboratory. What results would you expect to observe?
I. Decreased ability of the tissue to relax after contraction
II. Increased concentration of ADP in the mitochondrial matrix
III. Increased concentration of lactic acid in the cytosol
IV. Increased concentration of NADH and FADH2 in the mitochondrial matrix
I, II, and IV
II, III, IV
I and II
I and IV
I, II, and III
Transcribed Image Text:Question 23 2 pts As it turns out, arsenic is a competitive inhibitor of pyruvate dehydrogenase. Suppose you add arsenic to human muscle tissue in a laboratory. What results would you expect to observe? I. Decreased ability of the tissue to relax after contraction II. Increased concentration of ADP in the mitochondrial matrix III. Increased concentration of lactic acid in the cytosol IV. Increased concentration of NADH and FADH2 in the mitochondrial matrix I, II, and IV II, III, IV I and II I and IV I, II, and III
Expert Solution
Step 1

Pyruvate dehydrogenase converts pyruvate to acetyl-CoA in the mitochondrial matrix. The reaction uses the NAD+ cofactor to produce NADH and releases 1 molecule of carbon dioxide.

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