Question 3. The Lyme disease spirochete, Borrelia burgdorferi, abundantly produces outer surface lipoprotein A (OspA) in the tick vector but downregulates OspA in mammals in order to evade the immune system and maintain its natural enzootic cycle. The protein BosR is thought to regulate OspA. Below is a protein gel from the spirocete in a tick on the left and from the spirocete in a mammal on the right. From this gel, how is BosR regulating the expression of OspA? Please explain your answer. KD 37- 20- 20- 250- 75- 50- 37- 25- 20- 15- - FlaB A-BosR -OspC -OspA
Proteins
We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.
Protein Expression
The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.
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