Question 3 Without oxygen (O2) present, glycolysis normally cannot continue because: There is no more NAD+ being produced The mitochondria die from lack of oxygen O2 is used up during glycolysis enzymes can only function if O2 is present ATP formation requires O2
Question 3
Without oxygen (O2) present, glycolysis normally cannot continue because:
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There is no more NAD+ being produced
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The mitochondria die from lack of oxygen
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O2 is used up during glycolysis
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enzymes can only function if O2 is present
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ATP formation requires O2
Glycolysis occurs in two stages:
Stage I: This stage catalyzes the splitting of glucose molecule (C6) into two phosphoglyceraldehyde (C3) molecules. It consists of four consecutive reactions. Two ATP's are used per glucose metabolized.
Glucose + 2ATP -------> 2PGALD + 2ADP
Stage II: This stage catalyzes the oxidation of phosphoglyceraldehyde to pyruvate. It consists of five consecutive reactions. Stage II generates four ATPs per glucose metabolized hence net yield of ATP is 2.
2PGALD + 2Pi + 4 ADP + 2NAD+ ---------> 2 Pyruvate + 4 ATP +2 NADH + 2 H+
Glycolysis: Glucose+2ADP+2Pi 2NAD+ ------->2 Pyruvate + 2ATP+2 NADH+ 2 H+
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