Question 2: lon channels are the key to cell signaling in the body. The voltage gated calcium channels discussed in question one are a part of that. These systems are in delicate balance, keeping ion concentrations around the cell at a specific level so that an electrical signal can travel, in this case, down a skeletal muscle, and cause a contraction. Both hypokalemic (too few ions) periodic paralysis and hyperkalemic (too many ions) periodic paralysis are caused by mutations to the CACNA1S gene. If a mutation created a hyperkalemic periodic paralysis phenotype, that mutation could be characterized as for the CACNA1s gene A. Gain of Function B. Loss of Function C. Null D. Silent If a mutation created a hypokalemic periodic paralysis phenotype, that mutation could be characterized as for the CACNA1s gene A. Gain of Function B. Loss of Function C. Null D. Silent

Question 2: lon channels are the key to cell signaling in the body. The voltage gated calcium channels discussed in question one are a part of that. These systems are in delicate balance, keeping ion concentrations around the cell at a specific level so that an electrical signal can travel, in this case, down a skeletal muscle, and cause a contraction. Both hypokalemic (too few ions) periodic paralysis and hyperkalemic (too many ions) periodic paralysis are caused by mutations to the CACNA1S gene. If a mutation created a hyperkalemic periodic paralysis phenotype, that mutation could be characterized as for the CACNA1s gene A. Gain of Function B. Loss of Function C. Null D. Silent If a mutation created a hypokalemic periodic paralysis phenotype, that mutation could be characterized as for the CACNA1s gene A. Gain of Function B. Loss of Function C. Null D. Silent

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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During neuronal signaling, a change in membrane potential will cause sodium channelsto open and let Na+ ions diffuse down their concentration gradient into the cell. Whichof the following helps establish the concentration gradient necessary for this process tooccur?
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question in image, thanks so much! :D
When a cell membrane potential shifts from -70mV to -90mV we say the membrane has: depolarized repolarized hyperpolarized polarized GOOO0
Conditions: [Na+] outside = .3 mM [Na+] inside the presynaptic cell = .01 mM [dopamine] inside = .5 mM [dopamine] outside = .001 mM ΔGinward = RT ln [X] inside/[X] outside + z F Vm F = 23,000 cal/mol V R = 1.987 cal/ mol K Membrane potential is .07 V Temperature is 273 K Using the information above and image please answer these questions : Is the concentration of sodium higher on the outside or the inside of the presynaptic cell? Would the movement of sodium be active or passive moving OUT of the presynaptic cell? SHOW your work.
Both rhodopsin in vision and the muscarinic acetylcholine receptor in cardiac muscle are coupled to ion channels via G proteins. Describe the similarities and differences between these two systems.
11.
What is the intracellular voltage for Cl- if the intracellular concentration was 5 mM and the extracellular concentration was 130 mM. Write the voltage as a number in mV inside the cell relative to that outside, eg. -72 or + 90. Question 2. What is the intracellular voltage for Ca++ if the intracellular concentration was 0.0008 mM and the extracellular concentration was 0.6 mM. Write the voltage as a number in mV inside the cell relative to that outside, eg. -72 or +90. Round to the nearest milli Volt.
QUESTION 18 Which of the following are features of the basement membrane but not the ECM? A Contains both laminins and fibrillar collagens (e.g. collagen I and III). B Contains all types of collagens. C Contains both laminin and network-forming collagens (e.g. collagen IV). D Contains network-forming collagens (e.g. collagen IV) E Contains fibrillar collagens (e.g. collagen I and III).
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Myasthenia gravis is a disease that leads to a marked decrease in the number of acetylcholine (Ach) receptors at the neuromuscular junction. As a result, suppose only about 200 (instead of 2000) Ach receptor-channels are opened by each quantum of Ach. The Ach-gated channels that survive operate normally and each cause a depolarization of about 0.25 x 10-3 mV when open. The function of the presynaptic terminal is normal and an action potential will cause the release of 100 quanta of neurotransmitter. Part a.) For a patient with myasthenia gravis, what would be the size (in mV) of a miniature excitatory post-synaptic potential (or that associated with one quantum of Ach)? a.) 0.05 mv b.) 0.25x10-4 mv c.) 0.25x10-3 mv d.) 0.5x10-3 mv e.) 0.5 mv Part b.) For a patient with myasthenia gravis, what would be the size (in mV) of the full excitatory post synaptic potential consequent to the entry of an action potential into the presynaptic terminal of the neuromuscular junction? a.) 70 mv…
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