Q3: For a new mutation arising in the human BRCA1 gene (designated BRCA1-A4), there is a linked allele, RS651118 ~150,000bp away on the same chromosome. Assume recombination rate (r) is 1% for every megabase. After 25 generations, what is the estimated linkage disequilibrium, D, observed between these two alleles? How much has D changed? Use five decimal places in your calculations.

Q3: For a new mutation arising in the human BRCA1 gene (designated BRCA1-A4), there is a linked allele, RS651118 ~150,000bp away on the same chromosome. Assume recombination rate (r) is 1% for every megabase. After 25 generations, what is the estimated linkage disequilibrium, D, observed between these two alleles? How much has D changed? Use five decimal places in your calculations.

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter12: Mendel's Experiments And Heredity

Section: Chapter Questions

Problem 26CTQ: The gene for flower position in pea plants exists as axial or terminal alleles. Given that axial is...

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