Now we will move on to module 3, where we will examine autoradiographs produced from Sanger sequencing the p53 gene from tissue samples from Valerie's children. Determine the sequences based on the following simulated autoradiographs: A I || 1. Wild-type: GT 11 I B. What the sequence of this portion of the wild-type p53 gene? || 3. Sheila: D. What is the sequence of this portion of Sheila's p53 gene? E. Do Justin or Sheila have a mutation in the p53 gene?
Now we will move on to module 3, where we will examine autoradiographs produced from Sanger sequencing the p53 gene from tissue samples from Valerie's children. Determine the sequences based on the following simulated autoradiographs: A I || 1. Wild-type: GT 11 I B. What the sequence of this portion of the wild-type p53 gene? || 3. Sheila: D. What is the sequence of this portion of Sheila's p53 gene? E. Do Justin or Sheila have a mutation in the p53 gene?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
can u help with q. 3? Thank you

Transcribed Image Text:Now we will move on to module 3, where we will examine autoradiographs produced from Sanger sequencing
the p53 gene from tissue samples from Valerie's children.
Determine the sequences based on the following simulated autoradiographs:
A C G т
1. Wild-type:
B. What is the sequence of this portion of the wild-type p53 gene?
T
A CGT
|
2. Justin:
=
C. What is the sequence for this portion of Justin's p53 gene?
3.
I
A C GT
Sheila:
=
D. What is the sequence of this portion of Sheila's p53 gene?
E. Do Justin or Sheila have a mutation in the p53 gene?
Expert Solution

Step 1
The term DNA sequencing in compasses method for determining the order of the nucleotide bases, adenine, guanine, Cytosine and Thymine in a DNA molecule. The methodologeis for DNA sequencing are as follows:
1. Chain termination method,
2. Chemical degradation method,
3. Pyrosequencing method.
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