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Analyzing polymorphism and divergence data for a gene, you calculate the following McDonald-Kreitman table. Polymorp. Fixed Synonymous 40 80 Non-synonymous 20 80 A) Based on the ratio of non-synonymous to synonymous poly- morphisms, and given the 80 synonymous substitutions, how many nonsynymous substitutions would you expect if this gene were evolving neutrally? B) Is this table consistent with the gene evolving neutrally? If not what could explain the results?

Analyzing polymorphism and divergence data for a gene, you calculate the following McDonald-Kreitman table. Polymorp. Fixed Synonymous 40 80 Non-synonymous 20 80 A) Based on the ratio of non-synonymous to synonymous poly- morphisms, and given the 80 synonymous substitutions, how many nonsynymous substitutions would you expect if this gene were evolving neutrally? B) Is this table consistent with the gene evolving neutrally? If not what could explain the results?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Analyzing polymorphism and divergence data for a gene, you calculate the following McDonald-Kreitman table. Polymorp. Fixed Synonymous 40 Non-synonymous 20 A) Based on the ratio of non-synonymous to synonymous poly- morphisms, and given the 80 synonymous substitutions, how many nonsynymous substitutions would you expect if this gene were evolving neutrally? B) Is this table consistent with the gene evolving neutrally? If not what could explain the results? 80 80
Transcribed Image Text:Analyzing polymorphism and divergence data for a gene, you calculate the following McDonald-Kreitman table. Polymorp. Fixed Synonymous 40 Non-synonymous 20 A) Based on the ratio of non-synonymous to synonymous poly- morphisms, and given the 80 synonymous substitutions, how many nonsynymous substitutions would you expect if this gene were evolving neutrally? B) Is this table consistent with the gene evolving neutrally? If not what could explain the results? 80 80
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