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Klunk et al. (2022) recently completed a genome-wide association study (GWAS) using ancient DNA to find genes associated with survival of the medieval bubonic plague pandemic. They found that a C/T polymorphism at SNP rs2549794 near the ERAP2 gene was significantly associated with survival during the plague pandemic. Frequency of the C allele at rs2549794 was significantly higher in individuals who survived the plague than in individuals who died from the plague. (See the figure below.) ERAP2 encodes a protein that functions in immune responses. Which of the following is the best conclusion from these data? a b с d The C allele at SNP rs2549794 made people more susceptible to the plague. d The C allele at SNP rs2549794 made people less likely to die from the plague. C allele frequency 0.81 0.7- Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. 0.6 0.5 ERAP1/ERAP2: rs2549794 0.4 0.3- ERAP 2 alleles containing a C at SNP rs2549794 made people more susceptible to the plague. ERAP 2 alleles containing a C at SNP rs2549794 made people less likely to die from the plague. BD After BD

Klunk et al. (2022) recently completed a genome-wide association study (GWAS) using ancient DNA to find genes associated with survival of the medieval bubonic plague pandemic. They found that a C/T polymorphism at SNP rs2549794 near the ERAP2 gene was significantly associated with survival during the plague pandemic. Frequency of the C allele at rs2549794 was significantly higher in individuals who survived the plague than in individuals who died from the plague. (See the figure below.) ERAP2 encodes a protein that functions in immune responses. Which of the following is the best conclusion from these data? a b с d The C allele at SNP rs2549794 made people more susceptible to the plague. d The C allele at SNP rs2549794 made people less likely to die from the plague. C allele frequency 0.81 0.7- Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. 0.6 0.5 ERAP1/ERAP2: rs2549794 0.4 0.3- ERAP 2 alleles containing a C at SNP rs2549794 made people more susceptible to the plague. ERAP 2 alleles containing a C at SNP rs2549794 made people less likely to die from the plague. BD After BD

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Klunk et al. (2022) recently completed a genome-wide association study (GWAS) using ancient DNA to find genes associated with survival of the medieval bubonic plague pandemic. They found that a C/T polymorphism at SNP rs2549794 near the ERAP2 gene was significantly associated with survival during the plague pandemic. Frequency of the C allele at rs2549794 was significantly higher in individuals who survived the plague than in individuals who died from the plague. (See the figure below.) ERAP2 encodes a protein that functions in immune responses. Which of the following is the best conclusion from these data? a B The C allele at SNP rs2549794 made people more susceptible to the plague. d The C allele at SNP rs2549794 made people less likely to die from the plague. C allele frequency 0.81 0.7 0.6- 0.5- Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. 0.4 ERAP1/ERAP2: rs2549794 0.3- с ERAP 2 alleles containing a C at SNP rs2549794 made people more susceptible to the plague. ERAP 2 alleles containing a C at SNP rs2549794 made people less likely to die from the plague. BD Į After BD
Transcribed Image Text:Klunk et al. (2022) recently completed a genome-wide association study (GWAS) using ancient DNA to find genes associated with survival of the medieval bubonic plague pandemic. They found that a C/T polymorphism at SNP rs2549794 near the ERAP2 gene was significantly associated with survival during the plague pandemic. Frequency of the C allele at rs2549794 was significantly higher in individuals who survived the plague than in individuals who died from the plague. (See the figure below.) ERAP2 encodes a protein that functions in immune responses. Which of the following is the best conclusion from these data? a B The C allele at SNP rs2549794 made people more susceptible to the plague. d The C allele at SNP rs2549794 made people less likely to die from the plague. C allele frequency 0.81 0.7 0.6- 0.5- Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. 0.4 ERAP1/ERAP2: rs2549794 0.3- с ERAP 2 alleles containing a C at SNP rs2549794 made people more susceptible to the plague. ERAP 2 alleles containing a C at SNP rs2549794 made people less likely to die from the plague. BD Į After BD
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