Q-7. Receptor Mediated Endocytosis a. Which protein depicted is a small monomeric GPTase? b. Are all vesicle coats made of Clathrin? Explain. c. Are all adaptins alike? d. Clathrin triskelions self- assemble upon binding a cargo-receptor-adaptin complex. What causes them to diassemble at the end when the vesicle gets pinched off? e. This diagram depicts endocytosis, does the same mechanism apply to the secretory pathway (in reverse?)
Q-7. Receptor Mediated Endocytosis a. Which protein depicted is a small monomeric GPTase? b. Are all vesicle coats made of Clathrin? Explain. c. Are all adaptins alike? d. Clathrin triskelions self- assemble upon binding a cargo-receptor-adaptin complex. What causes them to diassemble at the end when the vesicle gets pinched off? e. This diagram depicts endocytosis, does the same mechanism apply to the secretory pathway (in reverse?)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:coated
vesicle
clathrin coat
UNCOATING
VESICLE
FORMATION
adaptin
cargo
receptor
adaptin
naked transport
vesicle
dynamin
CYTOSOL
EXTRACELLULAR SPACE
cargo molecules
Q-7. Receptor Mediated Endocytosis
a. Which protein depicted is a small monomeric GPTase?
b. Are all vesicle coats made of Clathrin? Explain.
c. Are all adaptins alike?
d. Clathrin triskelions self- assemble upon binding a cargo-receptor-adaptin complex. What causes them to
diassemble at the end when the vesicle gets pinched off?
e. This diagram depicts endocytosis, does the same mechanism apply to the secretory pathway (in reverse?)
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