Predict the outcome of the following hypothetical experiments and be sure to explain and be rational in addition to proposing the probable outcome of the experiment: -> you alter the Rab-GDI binding site so that it cannot interact with Rab-GDP
Predict the outcome of the following hypothetical experiments and be sure to explain and be rational in addition to proposing the probable outcome of the experiment:
-> you alter the Rab-GDI binding site so that it cannot interact with Rab-GDP
-> you have identified a drug that can specifically deplete PI(4)P from the trans-Golgi of the cell. When you treat cells with this drug you hypothesize....
-> while investigating novel anti-cancer drugs you identify a compound that disrupts y-tubulin localization to the centrosome and disperses it throughout the cytosol. Why might this compound be a useful anti-cancer agent?
Three fictitious studies are given, all of which include medication treatments or molecular changes in cellular settings. Expected results and their implications are examined, taking into account the effects of altering essential biological components and their uses in the treatment of disease, particularly the creation of anti-cancer drugs.
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