Practice Pedigree Problem help. I am confused so please show. Label Phenotypes and genotypes as you go about the Pedigree (and whatever else might be required)! Thank you again for your help, these questions confuse me). Hair or fur length in cats is controlled by a single, autosomal gene; the short hair-allele is dominant to the allele for long hair. Hair color is produced by a different gene which is located on the X chromosome. One allele for this sex-linked gene produces yellow, while an alternate allele produces black fur color; individuals which are heterozygous for these alleles are calico or tortiseshell in color. a). If a long-haired, black male is mated with a calico female homozygous for short hair, what kind of kittens will be produced in the F1generation? Give both genotypes and phenotypes; express the genotypes both symbolically and in words.

Practice Pedigree Problem help. I am confused so please show. Label Phenotypes and genotypes as you go about the Pedigree (and whatever else might be required)! Thank you again for your help, these questions confuse me). Hair or fur length in cats is controlled by a single, autosomal gene; the short hair-allele is dominant to the allele for long hair. Hair color is produced by a different gene which is located on the X chromosome. One allele for this sex-linked gene produces yellow, while an alternate allele produces black fur color; individuals which are heterozygous for these alleles are calico or tortiseshell in color. a). If a long-haired, black male is mated with a calico female homozygous for short hair, what kind of kittens will be produced in the F1generation? Give both genotypes and phenotypes; express the genotypes both symbolically and in words.

Name: Practice Pedigree Problem help. I am confused so please show. Label Ph
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Description: Practice Pedigree Problem help. I am confused so please show. Label Phenotypes and genotypes as you go about the Pedigree (and whatever else might be required)! Thank you again for your help, these questions confuse me).Hair or fur length in cats is

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 1CS: A couple was referred for genetic counseling because they wanted to know the chances of having a...

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A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. Should the parents be concerned about the heterozygous condition as well as the homozygous mutant condition?
A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What if the couple wanted prenatal testing so that a normal fetus could be aborted?
Please help finding the chance. Correct answer is 1/32
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PEDIGREES: Problem (continued) This pedigree shows the inheritance of cystic fibrosis in this family. I • QUESTIONS ••. 5. What is the genotype of individual II-3? Use the letter "f" to 1 2 represent the disease allele. II 1 2 3 6. Individuals II-I and II-2 are sisters. Explain how it is possible for one sister to have cystic fibrosis but NOT the other. III 1 2 3
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