Please answer questions 2-4 thank you! Page <2. Club foot is one of the most common congenital skeletal abnormalities, with a worldwide incidence of about 1 in 1000births. Both genetic and nongenetic factors are thought to be responsible for club foot. C.A. Gurnett et al.(2008. American Journal of Human Genetics 83:616-622) identified a family in which club foot was inherited as anautosomal dominant trait with incomplete penetrance. They discovered a mutation in the PITXI gene that coused clubfoot in this family. Through DNA testing, they determined that 11 people in the family carried the PITXI mutation, butonly 8 of these people had club foot. What is the penetrance of the PITXI mutation in this family?is3. Assume that long ear lobes in humans are an autosomal dominant trait that exhibits 30% penetrance. A person whoheterozygous for long ear lobes mates with a person who is homozygous for normal ear lobes. What is the probabilitythat their first child will have long ear lobes?4. In chickens, comb shepe is determined by alleles at two loci (R, rand P. p. A wainut comb is produced when at leastone dominant llele Ris present at one locus and at least one dominant aliele Pis present st a second locusgenotype RP). A rose comb is produced when at least one dominant allele is present et the first locus and tworecessive alleies are present at the second locus (genotype R op). A pes comb is produced when two recessive allelesare present at the first locus and at lest one dominant allele is present at the second (genotype rr P). If two recessiveBleles ere present at the first and at the second locus (rr pp), singie combis produced. Progeny with what types ofcombs and in whnat proportions will resuit from the tolowing crosses? What genetic principie is this an exemple ofplus (o) sad (5) aso. (a) anuem(e adeus owesRRPP eed Rrpe Rr D

Answered: out 1 in 1 d as an pused club ation,…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Please answer questions 2-4 thank you!

Page <
2. Club foot is one of the most common congenital skeletal abnormalities, with a worldwide incidence of about 1 in 1000
births. Both genetic and nongenetic factors are thought to be responsible for club foot. C.A. Gurnett et al.
(2008. American Journal of Human Genetics 83:616-622) identified a family in which club foot was inherited as an
autosomal dominant trait with incomplete penetrance. They discovered a mutation in the PITXI gene that coused club
foot in this family. Through DNA testing, they determined that 11 people in the family carried the PITXI mutation, but
only 8 of these people had club foot. What is the penetrance of the PITXI mutation in this family?
is
3. Assume that long ear lobes in humans are an autosomal dominant trait that exhibits 30% penetrance. A person who
heterozygous for long ear lobes mates with a person who is homozygous for normal ear lobes. What is the probability
that their first child will have long ear lobes?
4. In chickens, comb shepe is determined by alleles at two loci (R, rand P. p. A wainut comb is produced when at least
one dominant llele Ris present at one locus and at least one dominant aliele Pis present st a second locus
genotype RP). A rose comb is produced when at least one dominant allele is present et the first locus and two
recessive alleies are present at the second locus (genotype R op). A pes comb is produced when two recessive alleles
are present at the first locus and at lest one dominant allele is present at the second (genotype rr P). If two recessive
Bleles ere present at the first and at the second locus (rr pp), singie combis produced. Progeny with what types of
combs and in whnat proportions will resuit from the tolowing crosses? What genetic principie is this an exemple of
plus (o) sad (5) aso. (a) anuem(e adeus owes
RRPP ee
d Rrpe Rr D

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In some cases, clubfoot can be associated with other abnormalities of the skeleton that are present of birth(congenital), such as spina bifida, a birth defect that occurs when the spine and spinal cord don't develop or close property.In biology, the ear lobes of a human are generally described as a smooth, muscular outermost portion of the ear. It has substantial blood circulation as well as several nervous terminals. In humans, the major purpose of earlobe, is to keep the ears warmer and assist in the maintenence of stability.

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