Pioglitazone, a drug used to treat diabetes, causes some membrane-embedded portions of mitochondrial Complex I to separate from the rest of the protein that includes the matrix “arm.” Predict the effect of pioglitazone on electron transport and ATP production. The protonmotive force is decreased, leading to less ATP produced by ATP synthase

Q: Explain how Ca2+, NOS/RNS and mitochondrial membrane transfer problems are inter-related and how/why…

A: Reactive nitrogen species (RNS) are the antimicrobial molecules derived from nitric oxide (•NO) and…

Q: electron transport chain,

A: The ETC stands for Electron transport chain process that occurs in the mitochondria. It helps to…

Q: Oxidative phosphorylation generates ATP using the reducing power of [ Select ] ["NADH, FADH2",…

A: Oxidative phosphorylation is the process in which ATP is formed as a result of the transfer of…

Q: Referring to the figure below, explain why NADH yields more ATP than FADH2 does.

A: The electron transport chain is a sequence of four protein complexes that connect redox events to…

Q: Would an increase in the concentration of oxygen affect the inhibitioncaused by cyanide? How would…

A:

Q: ajority of ATP production in aerobic cellular respiration occurs within the mitochondria during…

A: Mitochondria is the main organically for aerobic respiration. Cellular respiration is divided into…

Q: A new weight loss drug, Super Fat Melter, is introduced on the market but then quickly recalled…

A: The electron transport chain takes place in the inner membrane of mitochondria.

Q: If electron flow through the ETC stops, what happens to the proton gradient across the mitochondrial…

A: 1.If Electron flow through the ETC stops, proton gradient cannot be maintained i.e, less ATP will be…

Q: The fatty acid side chains of the phospholipids in the inner mitochondrial membrane exhibit a large…

A: Since you have posted multiple questions, we will provide the solution only to the first question as…

Q: For the Complex III in the electron transport chain:   Complex III step 1: UQH2 is oxidized in a 2…

A: In the question there are two separate processes mentioned Two electron process One Electron…

Q: Consider a 24:1 △­­cis-9 fatty acid in the mitochondrion. For each fatty acid given, determine the…

A: Fatty acids are (-COOH)carboxylic acids with hydrocarbon chains from 4 to 36 carbon long. These can…

Q: YA) All of the following satisfy the requirements of Complex V oxidative phosphorylation, EXCEPT…

A: The reduced electron carriers, NADH and FADH2 are produced as a byproduct of glycolysis. The…

Q: If actively respiring mitochondria are exposed to an inhibitor of ATP-ADP translocase, the…

A: ATP is the energy currency of the cell. It is produced via oxidative phosphorylation of ADP and Pi…

Q: In the process of electron and H transport in the mitochondrial inner membrane, which of the…

A: Mitochondria are the membrane-bound organelles that produce the energy required to power the various…

Q: For each of the following experiments, tell me whether you would expect the rate of O₂ consumption…

A: Oxidative phosphorylation is the process by which ATP is synthesized and is also coupled to the…

Q: The AG of the reaction C6H12O6 +602 --> 6CO2 + 6H₂O is -686 kcal/mol glucose The oxidation of…

A: For biological systems, free energy (G), enthalpy (H) and entropy (S) are related as : ∆G = ∆H - T∆S…

Q: Where is ATP produced by oxidative phosphorylation? (where is it located immediately after the…

A: Adenosine triphosphate (ATP)It is the source of energy for use in cellular level. Energy also stored…

Q: Which of the following drives the electron transfer from coenzyme Q to cytochrome c, which also…

A: 1. Electron transport chain occurs in the membrane of the mitochondria. There are many complexes…

Q: Which of the following best describes the specific gradients driving ATP synthesis in figures A and…

A: Various processes are utilized in carrying out various biochemical processes.

Q: What is the minimum voltage drop for individual electron transfer events in the mitochondrial…

A: The electron transport chain that occurs in mitochondria is present in a sequence of electron…

Q: Explain how the transfer of electrons from one electron transport chain complex to the next,…

A: According to the guidelines of Bartleby,"Since you have posted multiple questions, we will provide…

Q: Electron transfer translocates protons from the mitochondrial matrix to the external medium,…

A: The objective of the question is to understand the proton concentration in the mitochondrial matrix…

Q: About 30 ATP are produced per glucose molecule oxidized. What would happen to the yield of ATP per…

A: Oxidative Phosphorylation: Both oxidative phosphorylation and substrate-level phosphorylation…

Q: (A) What is the free energy yield associated with the transport of a proton from the mitochondrial…

A: Given,△G = RTlnKeq. Also given that pH of IMS is 1.4 units lower than pH of the matrix. R =…

Q: How much energy is required to pump a mole of protons in a mitochondria with the following…

A: Enzymes in the mitochondria function as proton pumps and generate an electrochemical gradient used…

Q: Calculate how many moles of ATP can be made in standard conditions when 1 mole of protons flow back…

A: The principal energy unit of cells, ATP provides the energy required for a variety of cellular…

Q: Recall that in order to move the phosphate required for ATP synthesis into the matrix, a proton is…

A: ATP synthase It is a protein that catalyzes the conversion of inorganic phosphate and adenosine…