OH OH 0₂ OH Which reaction below is likely coupled to the above reaction? ATP --> ADP ADP --> ATP OCOA-SH --> COA NAD+ --> NADH CoQ10 --> CoQ10H₂
OH OH 0₂ OH Which reaction below is likely coupled to the above reaction? ATP --> ADP ADP --> ATP OCOA-SH --> COA NAD+ --> NADH CoQ10 --> CoQ10H₂
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Organic Chemistry of Metabolic Pathways
Metabolic pathways allude to the arrangement of chemical catalyzed reactions that lead to the transformation of a substance into the final product. Metabolic pathways incorporate a progression of reaction where the substrate is changed continuously and the transitional metabolites are persistently recovered.
Glucogenesis
Glucogenesis is a metabolic pathway in which glucose is produced from carbon substrates that are not carbohydrates. This process is observed in plants, animals, fungi, bacteria and other micro organisms. The general definition for glucogenesis or gluconeogenesis is as follows,
Question
![**Understanding Coupled Reactions in Biochemistry**
In biochemical pathways, reactions often occur in pairs, known as coupled reactions. This is fundamental to understanding how cells harness and utilize energy.
### Example Reaction and Coupling
Consider the chemical reaction shown in the image, where a molecule undergoes oxidation in the presence of oxygen (O₂) to form a different molecule:
\[ \text{Reactant} \rightarrow \text{Product} \]
This reaction is identified by the transformation of a carboxylic acid group (indicated by the COOH group) which is a common reaction in metabolic pathways involving redox reactions.
### Coupled Reaction Options
The image provides multiple-choice options to identify which reaction is most likely to be coupled with the above reaction:
1. **ATP --> ADP**
2. **ADP --> ATP**
3. **CoA-SH --> CoA**
4. **NAD⁺ --> NADH**
5. **CoQ₁₀ --> CoQ₁₀H₂**
### Explanation
In biochemical systems, coupling often involves redox pairs or phosphorylation/dephosphorylation events to maintain energy balance and facilitate necessary cellular processes. For example:
- **NAD⁺ --> NADH**
This indicates the reduction of NAD⁺ to NADH, which typically couples with oxidation reactions, making it a probable match.
- **ATP --> ADP**
This indicates the release of energy, often coupled with processes that require energy.
Given the reactant is oxidized, the reduction of NAD⁺ to NADH is most likely coupled to balance the redox reaction.
**Conclusion:**
The most likely reaction to be coupled with the above oxidative reaction is:
\[ \mathbf{NAD^+ \rightarrow NADH} \]
This coupling ensures that the redox balance is maintained during the cellular metabolic processes. Understanding these reactions helps provide insight into how cells efficiently manage energy and biochemical transformations.
---
This content is intended for educational purposes, providing an understanding of reaction coupling in biochemical pathways.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F38d688d2-1b61-4170-a70a-b1328ea0535f%2Fe88df013-7eb8-4653-b06c-c4aea7786b3c%2Fwxv4ssi6_processed.png&w=3840&q=75)
Transcribed Image Text:**Understanding Coupled Reactions in Biochemistry**
In biochemical pathways, reactions often occur in pairs, known as coupled reactions. This is fundamental to understanding how cells harness and utilize energy.
### Example Reaction and Coupling
Consider the chemical reaction shown in the image, where a molecule undergoes oxidation in the presence of oxygen (O₂) to form a different molecule:
\[ \text{Reactant} \rightarrow \text{Product} \]
This reaction is identified by the transformation of a carboxylic acid group (indicated by the COOH group) which is a common reaction in metabolic pathways involving redox reactions.
### Coupled Reaction Options
The image provides multiple-choice options to identify which reaction is most likely to be coupled with the above reaction:
1. **ATP --> ADP**
2. **ADP --> ATP**
3. **CoA-SH --> CoA**
4. **NAD⁺ --> NADH**
5. **CoQ₁₀ --> CoQ₁₀H₂**
### Explanation
In biochemical systems, coupling often involves redox pairs or phosphorylation/dephosphorylation events to maintain energy balance and facilitate necessary cellular processes. For example:
- **NAD⁺ --> NADH**
This indicates the reduction of NAD⁺ to NADH, which typically couples with oxidation reactions, making it a probable match.
- **ATP --> ADP**
This indicates the release of energy, often coupled with processes that require energy.
Given the reactant is oxidized, the reduction of NAD⁺ to NADH is most likely coupled to balance the redox reaction.
**Conclusion:**
The most likely reaction to be coupled with the above oxidative reaction is:
\[ \mathbf{NAD^+ \rightarrow NADH} \]
This coupling ensures that the redox balance is maintained during the cellular metabolic processes. Understanding these reactions helps provide insight into how cells efficiently manage energy and biochemical transformations.
---
This content is intended for educational purposes, providing an understanding of reaction coupling in biochemical pathways.
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