Objective: using the outcome of genetic crosses, determine whether a mutations that cause the same phenotype are located in the same gene or different genes. 1. Three true breeding mutants with the same autosomal recessive disease phenotype were isolated. When crossed, mutants 1 and 2 showed complementation and mutations 1 and 3 showed non-complementation. | A) Fill in the pedigrees below to reflect this information. B) Using capital and small letters to represent different alleles, write the genotype of each individual in the blank beside the symbol. You can choose which letter(s) to use. Hint: You should be using the same 2 genes in both pedigrees. #1 X #2 Complementation #1 X #3 Non-Complementation 무 무 O O = AaBb #1x #2: AAbb x aaBB #1x #3: AaBb x AAbb = AaBb or AABb C) If the female and male from generation 2 of the two pedigrees above were to have offspring, what percent of their offspring would show the mutant phenotype?

Human Anatomy & Physiology (11th Edition)
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Objective: using the outcome of genetic crosses, determine whether a mutations that
cause the same phenotype are located in the same gene or different genes.
1. Three true breeding mutants with the same autosomal recessive disease phenotype
were isolated. When crossed, mutants 1 and 2 showed complementation and mutations
1 and 3 showed non-complementation.
A) Fill in the pedigrees below to reflect this information.
B) Using capital and small letters to represent different alleles, write the genotype of
each individual in the blank beside the symbol. You can choose which letter(s) to use.
Hint: You should be using the same 2 genes in both pedigrees.
# 1 X #2 Complementation
C
#1 x #2: AAbb x aaBB = AaBb
#1 x #3: AaBb x AAbb = AaBb or AABb
#1 X #3 Non-Complementation
o
C) If the female and male from generation 2 of the two pedigrees above were to have
offspring, what percent of their offspring would show the mutant phenotype?
T
Transcribed Image Text:Objective: using the outcome of genetic crosses, determine whether a mutations that cause the same phenotype are located in the same gene or different genes. 1. Three true breeding mutants with the same autosomal recessive disease phenotype were isolated. When crossed, mutants 1 and 2 showed complementation and mutations 1 and 3 showed non-complementation. A) Fill in the pedigrees below to reflect this information. B) Using capital and small letters to represent different alleles, write the genotype of each individual in the blank beside the symbol. You can choose which letter(s) to use. Hint: You should be using the same 2 genes in both pedigrees. # 1 X #2 Complementation C #1 x #2: AAbb x aaBB = AaBb #1 x #3: AaBb x AAbb = AaBb or AABb #1 X #3 Non-Complementation o C) If the female and male from generation 2 of the two pedigrees above were to have offspring, what percent of their offspring would show the mutant phenotype? T
Expert Solution
Step 1

Given 

All three are mutants 

Cross of 1 and 2 = complement 

Cross of one and 3 = non complement 

 

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