Nocodazole is a potent inhibitor of microtubule polymerization, which is required for formation of the mitotic spindle. By treating a population of mammalian cells with nocodazole for a time and then washing it out of the medium, we can synchronize the cell population. In the presence of nocodazole, where in the cell cycle do you expect the cells to accumulate? What mechanism do think is responsible for stopping cell-cycle progression when cells are treated with nocodazole? you

Q: At What Phase Is the Cell Cycle Arrested by an Inhibitor?

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Q: Describe the mammalian cell cycle briefly. In your work, include a description of how cyclins and…

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A:

Q: kinases/phosphatases OR proteasomes ensures proper rates of cell division.

A:

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A: Cell signalling

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Q: What are checkpoints? List some of the important checkpoints in the cell cycle.

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Q: Describe how cyclins and cyclin-dependent kinases are related. How do these molecules help regulate…

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A:

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.