A cell in M phase with chromosomes not properly connected to the spindle apparatus should delay the completion of M phase by .. a) inhibiting the phosphatase that would normally activate M-Cdk O b) blocking M-Cdk activity with an inhibitory protein O c) reducing M-Cdk activity by degrading its cyclin partner d) preventing the actions of APC
A cell in M phase with chromosomes not properly connected to the spindle apparatus should delay the completion of M phase by .. a) inhibiting the phosphatase that would normally activate M-Cdk O b) blocking M-Cdk activity with an inhibitory protein O c) reducing M-Cdk activity by degrading its cyclin partner d) preventing the actions of APC
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:A cell in M phase with chromosomes not properly connected to the spindle apparatus
should delay the completion of M phase by ...
a) inhibiting the phosphatase that would normally activate M-Cdk
b) blocking M-Cdk activity with an inhibitory protein
c) reducing M-Cdk activity by degrading its cyclin partner
O d) preventing the actions of APC

Transcribed Image Text:Irradiation of mammalian cells to damage DNA will usually cause them to stop dividing
and arrest at the G1/S checkpoint.
Place the following events in the order.
halt of cell cycle at G1-S transition
translation of p21 mRNA
stabilization and activation of p53 protein
binding of p21 protein to G1/S-Cdk and S-Cdk
P53- regulated transcription of p21
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