NaCl (Mr = 58.443 g/mol)   2.5 M Tris-Cl, pH 8 oplossing / solution (1 Litre)   EDTA, sodium salt (Mr = 380.2 g/mol)   10 % Sodium dodecyl sulfate solution   Proteinase K solution (50 mg dissolved in 1 ml ddH2O) You need a digestion buffer consisting of the following:   15 mM NaCl   75 mM Tris-Cl, pH 8   16 mM EDTA, pH 8   0.8 % Sodium dodecyl sulfate   0.75 mg/ml proteinase K   Calculate:  How will you prepare 500 ml of the digestion buffer? Show all your steps and calculations and remember to explain how exactly you will make it up.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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NaCl (Mr = 58.443 g/mol)

  2.5 M Tris-Cl, pH 8 oplossing / solution (1 Litre)

  EDTA, sodium salt (Mr = 380.2 g/mol)

  10 % Sodium dodecyl sulfate solution

  Proteinase K solution (50 mg dissolved in 1 ml ddH2O)

You need a digestion buffer consisting of the following:

  15 mM NaCl

  75 mM Tris-Cl, pH 8

  16 mM EDTA, pH 8

  0.8 % Sodium dodecyl sulfate

  0.75 mg/ml proteinase K

 

Calculate: 
How will you prepare 500 ml of the digestion buffer? Show all your steps and calculations and remember to explain how exactly you will make it up.
 
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