12- 10- 8- 6- 4- 2- 0- 20 40 60 80 Volume of NaOH (mL) Hd

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Consider the following pH titration curve of a diprotic acid.  What is the approximate values for pka 1 and pka 2?

the curve is attached below.

The image displays a titration curve graph illustrating the change in pH as a function of the volume of NaOH added, measured in milliliters (mL). The x-axis represents the Volume of NaOH (mL) ranging from 0 to 80, while the y-axis denotes the pH level, which spans from 0 to 14.

Key Features of the Graph:

1. **Starting Point**: At 0 mL of NaOH, the pH is approximately 2, indicating an acidic solution.

2. **First Buffer Region**: As NaOH is added, the pH gradually increases, demonstrating a gentle slope until around 20 mL.

3. **First Equivalence Point**: A steep rise in pH occurs near 25 mL, indicating the neutralization of an equivalent amount of acid and base. The pH rapidly moves towards a more basic value.

4. **Second Equivalence Point**: Around 60 mL of added NaOH, there is another sharp increase in pH, signifying a second equivalence point, where another significant neutralization event occurs.

5. **Final Region**: Beyond this point, the curve levels off as more NaOH is added, reaching a pH close to 13, indicative of an excess of base in the solution.

This graph is typically used in the context of acid-base titrations, demonstrating the titration of a diprotic acid with a strong base, such as sodium hydroxide (NaOH). The two equivalence points reflect the two stages of hydrogen ion donation by the diprotic acid.
Transcribed Image Text:The image displays a titration curve graph illustrating the change in pH as a function of the volume of NaOH added, measured in milliliters (mL). The x-axis represents the Volume of NaOH (mL) ranging from 0 to 80, while the y-axis denotes the pH level, which spans from 0 to 14. Key Features of the Graph: 1. **Starting Point**: At 0 mL of NaOH, the pH is approximately 2, indicating an acidic solution. 2. **First Buffer Region**: As NaOH is added, the pH gradually increases, demonstrating a gentle slope until around 20 mL. 3. **First Equivalence Point**: A steep rise in pH occurs near 25 mL, indicating the neutralization of an equivalent amount of acid and base. The pH rapidly moves towards a more basic value. 4. **Second Equivalence Point**: Around 60 mL of added NaOH, there is another sharp increase in pH, signifying a second equivalence point, where another significant neutralization event occurs. 5. **Final Region**: Beyond this point, the curve levels off as more NaOH is added, reaching a pH close to 13, indicative of an excess of base in the solution. This graph is typically used in the context of acid-base titrations, demonstrating the titration of a diprotic acid with a strong base, such as sodium hydroxide (NaOH). The two equivalence points reflect the two stages of hydrogen ion donation by the diprotic acid.
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