Mitochondrial outer membrane permeabilization (MOMP) includes: Question 10 options: a) mitochondrial outer membranes are disrupted. b) caspases activation in either intrinsic or extrinsic pathway. c) cytochrome c release. d) All of the above. e) Only (a) and (c)
Mitochondrial outer membrane permeabilization (MOMP) includes:
Question 10 options:
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Mitochondria are highly specialized membrane-bound cell organelles found in the cells of eukaryotic organisms, such as animals, plants, and fungi. Mitochondria are the organelles that serve as the site of energy synthesis in the cell due to the presence of specific membrane proteins present in the inner mitochondrial membrane. The two membranes of mitochondria are an outer membrane and an inner membrane. The inner membrane contains numerous folds called cristae, which increase the surface area for energy production. Mitochondria have their own DNA and can replicate independently within the cell.
While mitochondria are typically associated with energy production and cell support, they also play a vital role in programmed cell death (apoptosis). Mitochondrial Outer Membrane Permeabilization (MOMP) is a significant step in apoptosis, leading to the release of pro-apoptotic factors from the mitochondrial intermembrane space to the cytosol.
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